Thiazide Diuretics and Hyponatremia

CEimpact Podcast

Hyponatremia is a side effect of most diuretics but the incidence from thiazides is unknown. Join host, Geoff Wall, as he evaluates a new study from Denmark evaluating hyponatremia and thiazides.
The GameChanger
Thiazide diuretics are considered first-line therapy but electrolyte side effects are underevaluated. A new study suggests hyponatremia is significantly more common than previously reported, especially in the elderly.
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
Reference
Andersson NW, Wohlfahrt J, Feenstra B, et al. Cumulative Incidence of Thiazide-Induced Hyponatremia: A Population-Based Cohort Study. Ann Intern Med. 2023 Dec 19. doi: 10.7326/M23-1989. Epub ahead of print. PMID: 38109740.
https://www.acpjournals.org/doi/abs/10.7326/M23-1989?journalCode=aim

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CPE Information

Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Discuss the use of thiazides in hypertension and their adverse effects
2. Assess the strengths and weaknesses of the Andersson et al study
0.05 CEU/0.5 Hr
UAN: 0107-0000-24-032-H01-P
Initial release date: 1/15/2024
Expiration date: 1/15/2025
Additional CPE details can be found here.

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Kapitel

1. Thiazide Diuretics and Hyponatremia (00:00:00)

2. Thiazide-Induced Hyponatremia Incidence Study (00:00:08)

3. Thiazide Diuretics and Risk of Hyponatremia (00:15:42)