Beste Venous Disease Podcasts (2024)

1
CD8+ T-cell differentiation and treatment response in AML; ATM germline pathogenic variants affect cancer outcomes in ataxia-telangiectasia; efficacy of a selective menin-KMT2A inhibitor in KMT2A- and ... 22:42

2d ago22:42

22:42

In this week's episode we’ll discuss how CD8+ T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia; learn more about the effect of ATM germline pathogenic variants on the outcomes in children with ataxia-telangiectasia and hematological malignancies; and discuss the preclinical efficacy of a potent, selective m…

1
Conversations in OB/GYN Edition | Hyperemesis 21:42

1d ago21:42

21:42

Hosts: Chatura Alur, M.D., M.P.H. | Meghan G. Theofiles, M.D. Guest: Margaret E. Long, M.D. Welcome to our OB/GYN mini-series! “Help me OB/GYN! You’re my only hope”. Today, we’re going to be talking about nausea and vomiting in pregnancy. We definitely see this in the healthcare setting, outside of the specialty office; and sometimes I wonder, do I…

1
Venous Thrombosis (DVT) 27:30

3d ago27:30

27:30

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Ana I. Casanegra, M.D., M.S. Venous thrombosis is an under diagnosed and potentially serious health condition, yet in many cases its preventable and certainly treatable when found. Its most serious potential complication is embolization, most commonly to the lung. As a medical condition, venous thromb…

1
TCR-T cells for post-HCT leukemia recurrence; platelets are the predominant source of procoagulant membranes in hemostasis; BR + R maintenance for MCL 18:10

9d ago18:10

18:10

In this week's episode we'll discuss HA-1-targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation. Next, we'll learn about how 4D intravital imaging in mice reveals the key role of platelets as a source of procoagulant membranes in hemostasis. Finally, we'll hear about modifications to a common i…

1
Conversations in OB/GYN Edition | Loss Management 38:59

8d ago38:59

38:59

Hosts: Chatura Alur, M.D., M.P.H. | Meghan G. Theofiles, M.D. Guest: Julie A. Lamppa, APRN, CNM Welcome to our OB/GYN mini-series! “Help me OB/GYN! You’re my only hope”. Today, we’re back with Julie A. Lamppa, APRN, CNM, director of our midwifery services at Mayo Clinic Rochester and director of the Early Pregnancy Care Clinic at Mayo Clinic in Roc…

1
Conversations in OB/GYN Edition | First Trimester Bleeding 40:37

10d ago40:37

40:37

Hosts: Chatura Alur, M.D., M.P.H. | Meghan G. Theofiles, M.D. Guest: Julie A. Lamppa, APRN, CNM Welcome to our OB/GYN mini-series! “Help me OB/GYN! You’re my only hope”. This podcast edition is specifically designed for the non-OB/GYN frontline provider. Today, we’re going to be addressing first trimester bleeding and we are joined by our content e…

1
Outcomes of younger patients with mantle cell lymphoma; M-protein assessment during maintenance therapy in multiple myeloma; in vivo CAR T-cell generation using lentiviral vectors 0:59

16d ago0:59

0:59

In this week's episode we’ll discuss the outcomes of younger patients with mantle cell lymphoma experiencing late relapse; learn more about mass spectrometry-based assessment of M-protein in peripheral blood during maintenance therapy in multiple myeloma and discuss in vivo CAR T-cell generation in non-human primates using lentiviral vectors. Featu…

1
Review Series on Factor XI 44:40

16d ago44:40

44:40

Introduced by Associate Editor Dr. Thomas Ortel, this bonus episode discusses the Review Series on Factor XI, published in volume 143 issue 15 of Blood Journal. Dr. Ortel is joined by contributing authors Owen McCarty, PhD, Gili Kenet, MD, and David Gailani, MD. Review Series Articles: Introduction to a review series on factor XI Biology of factor …

1
Working Effectively with Patients with Obsessive Compulsive Disorder (OCD) 29:24

18d ago29:24

29:24

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Craig N. Sawchuk, Ph.D., L.P. It’s estimated that 1 in 40 adults have obsessive compulsive disorder. Obsessions are repetitive, unwanted thoughts that are very difficult to control. They commonly cause distress and anxiety and are often focused on a specific theme such as germs and contamination. Comp…

1
Protective role of neonatal CMV infection in B-ALL; GVHD targets organoid-forming bile duct stem cells; seven-year outcomes for venetoclax-ibrutinib therapy in MCL 16:56

23d ago16:56

16:56

In this week's episode we'll learn how cytomegalovirus infection early in life depletes preleukemic cells in a mouse model of B-cell acute lymphoblastic leukemia. After that we'll discuss new research, where GVHD targets organoid-forming bile duct stem cells in a TGF-beta-dependent manner. Conversely, a TGF-beta inhibitor protects these stem cells …

1
Genes and Your Health Edition | GeneRx: Revolutionizing Primary Care with Pharmacogenomics 31:12

23d ago31:12

31:12

Host: Denise M. Dupras, M.D., Ph.D. Guest: Isa J. Houwink, M.D., Ph.D. Pharmacogenomics (PGx) is transforming everyday primary care practice. By using patients’ genetic profiles, providers are guiding more precise, personalized treatments. In this episode of Genes & Your Health podcast, primary care physicians Dr. Denise Dupra and Dr. Isa J. Houwin…

1
RISE for EQUITY Podcast | Women in Medicine 29:32

25d ago29:32

29:32

Brought to you by: Mayo Clinic Talks Podcast HOST: Nicole Nfonoyim-Hara GUESTS: Aminah Jatoi, M.D.; Yemi Sokumbi, M.D. On this episode of the RISE for Equity podcast, host Nicole Nfonoyim-Hara is joined by Dr. Aminah Jatoi and Dr. Yemi Sokumbi to discuss women in medicine. Drs. Jatoi and Sokumbi share their personal stories of deciding to practice …

1
Iron, HFE haemochromatosis, and infections; bispecific antibodies improve CAR T-cell response; determinants of outcome in NPM1-mutated AML 23:31

30d ago23:31

23:31

In this week's episode we'll learn about iron, HFE hemochromatosis, and infections. In this large, population-based study, both high and low levels of plasma iron and transferrin saturation were associated with increased risks of infection. Then, we'll discuss how bispecific antibodies improve CAR T-cell response in B-cell malignancies. In-vitro an…

1
Genes and Your Health Edition | Antisense Oligonucleotide (ASO) Therapeutics for Rare Genetic Disease 30:31

1M ago30:31

30:31

Host: Denise M. Dupras, M.D., Ph.D. Guest: Margot A. Cousin, Ph.D. This episode of Genes & Your Health provides a comprehensive look at how ASO (Antisense Oligonucleotide) therapy is paving the way for personalized medicine and offering new hope for patients with previously untreatable conditions. Margot A. Cousin, Ph.D., an Assistant Professor of …

1
Weight Changes Associated with Antidepressants 28:52

1M ago28:52

28:52

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Mark A. Frye, M.D. We have a variety of antidepressant medications available to us including SSRI’s, SNRI’s and others, and for the most part they’re very well tolerated by our patients. They are much better tolerated compared to some of our older options such as the tricyclic antidepressants and MAO …

1
Immune fitness and response to taclistamab in R/R multiple myeloma; BCR::ABL1 M244V mutation causes resistance to asciminib; HSCT and myocardial fibrosis in young patients with SCD 16:59

1M ago16:59

16:59

In this week's episode we’ll discuss how immune fitness impacts response to teclistamab in relapsed/refractory multiple myeloma; learn more about a new mechanism of resistance to asciminib conferred by the BCR::ABL1 M244V mutation, and discuss the impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell…

1
Genes & Your Health Edition | Microbiome and Ovarian Cancer 35:11

1M ago35:11

35:11

Host: Denise M. Dupras, M.D., Ph.D. Guest: Marina Walther-Antonio, Ph.D. Can microbe populations affect women’s health in areas like ovarian cancer or predicting pre-term delivery? Tune into this episode of Genes & Your Health with Marina Walther-Antonio, Ph.D., a microbiome researcher within Mayo Clinic's Center for Individualized Medicine, to lea…

1
Obesity Pharmacotherapy Management 21:18

1M ago21:18

21:18

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Kristina M. Thurber, Pharm D., R.PH. Obesity in the U.S. is reaching epidemic proportions. Managing our overweight patients has been challenging, with few being able to adopt and adhere to a healthy diet and exercise program. There is a class of medications that improves blood glucose in type 2 diabet…

1
Decitabine in older patients with AML; EPCR and sickle chronic kidney disease; lymphocyte depletion versus post-transplant cyclophosphamide for mismatched donor transplant for inborn errors of immunity ... 22:53

1M ago22:53

22:53

In this week's episode we’ll discuss the safety and efficacy of decitabine in older patients with AML; learn how heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice, and discuss the outcomes of treatment with HLA-mismatched HSCT with TCRab/CD19 lymphocyte depletion or post-HSCT cyclophosph…

1
Genes and Your Health Edition | Legal Aspects of Genetic Testing 35:10

1M ago35:10

35:10

Host: Denise M. Dupras, M.D., Ph.D. Guest: Jessica Kelly, JD Join our expert hosts as they delve into the intersection of genetic science and the legal landscape in this episode of Genes & Your Health. Jessica Kelly, J.D., and Denise M. Dupras, M.D., Ph.D., discuss the latest advancements in genetic research, personalized medicine, and how these in…

1
Sarcomas 18:11

2M ago18:11

18:11

Host: Darryl S. Chutka, M.D., [@chutkaMD] Guests: Steven I. Robinson, M.B.B.S., and Brittany L. Siontis, M.D. When you think of malignancies, sarcomas don’t usually come to mind. They are very uncommon and can occur in numerous locations. In addition, they can be very difficult to diagnose as the symptoms they produce are often very subtle. Approxi…

1
Wound Healing and Burn Care 31:49

2M ago31:49

31:49

This episode of Surgical Readings features an informative conversation led by Rick Greene, MD, FACS, with the associate editors for the Wound Healing and Burn Care issue. Laura Haines, MD, FACS, and Deepak Bharadia, MBBS, FACS, provide valuable perspectives on the management of non-healing wounds, prevention of hypertrophic scarring, and achieving …

1
Impact of MRD-negative on PFS in myeloma; IPSS-R down-staging before transplant in MDS; hereditary angioedema and venous thromboembolism 21:50

2M ago21:50

21:50

In this week's episode we'll discuss minimal residual disease as an intermediate clinical endpoint for multiple myeloma. Then, we'll learn about IPSS-R downstaging before transplant in MDS. Finally we'll hear about the connection between hereditary angioedema and venous thromboembolism. Featured Articles: EVIDENCE meta-analysis: evaluating minimal …

1
Genes and Your Health Edition | AI in Cardiology and Primary Care 33:50

2M ago33:50

33:50

Host: Denise M. Dupras, M.D., Ph.D. Guest: Peter A. Noseworthy, M.D., M.B.A. Rapid advances in artificial intelligence, or AI, are changing everyday medical practice. In this episode of Genes & Your Health, explore the transformative role of AI in cardiology and primary care practices. Don’t miss this fascinating episode of Genes & Your Health with…

1
From Head to Toe: How to Perform a Skin Exam 24:45

2M ago24:45

24:45

Host: Darryl S. Chutka, M.D., [@chutkaMD] Guest: Emma F. Johnson, M.D. For both men and women, skin cancer is the most common malignancy and unlike colon, breast and lung cancer, skin cancers should be visible as they exist on the exterior of our bodies. Primary care providers need to be proficient in examining the skin of our patients and recogniz…

1
Acalabrutinib, venetoclax and obinutuzumab in relapsed/refractory CLL; alternative donor transplantation for severe aplastic anemia; clonal relapse dynamics in AML following allogeneic HCT 23:32

2M ago23:32

23:32

In this week's episode we’ll discuss the safety and efficacy of acalabrutinib, venetoclax and obinutuzumab in relapsed/refractory CLL; learn more about alternative donor transplantation for severe aplastic anemia and discuss clonal relapse dynamics in acute myeloid leukemia following allogeneic hematopoietic cell transplantation. Featured Articles:…

1
Genes and your Health Edition | Answers from the Lab: Cell Free DNA and Testing for Cancer 29:16

2M ago29:16

29:16

Host: Denise M. Dupras, M.D., Ph.D. Guest: Aaron S. Mansfield, M.D. Can a simple blood draw diagnose cancer? Join this episode of Genes & Your Health with Aaron Mansfield, M.D., a Mayo Clinic medical oncologist whose focus is on thoracic malignancies and early therapeutics, as we discuss the science behind non-invasive cancer screening, how cell-fr…

1
RISE for EQUITY Podcast | Leadership in Healthcare: An Asian American Perspective 32:03

2M ago32:03

32:03

Brought to you by: Mayo Clinic Talks Podcast HOST: Nicole Nfonoyim-Hara GUEST: Amy Hara, M.D. On this episode of the RISE for Equity podcast, Dr. Amy Hara joins host Nicole Nfonoyim-Hara for an insightful discussion on the topic of leadership in healthcare. Dr. Hara, a member of the Mayo Clinic Board of Governors and Mayo Clinic Arizona’s Executive…

1
Clinical impact of CRh in AML; thrombosis features in a real-life PNH cohort; and restriction of SOX11 expression to EBV-negative Burkitt lymphomas 19:58

2M ago19:58

19:58

In this week's episode we'll learn about the clinical benefit of complete remission with partial hematological recovery, or CRh, in patients with Acute Myeloid Leukemia (AML) treated with molecularly targeted drugs. Then we'll hear about a large cohort of patients with PNH were studied to detail PNH-related thrombotic events, unravel determinants o…

1
Artificial Intelligence (AI) in Medicine: Part 2 21:48

2M ago21:48

21:48

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Jason D. Greenwood, M.D., M.S. Artificial intelligence is currently one of the most commonly discussed topics, but how does it relate to the practice of medicine? According to a recent publication in the Journal of the American Board of Family Medicine, “AI has the potential to fundamentally change th…

1
Artificial Intelligence (AI) in Medicine: Part 1 18:46

2M ago18:46

18:46

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Jason D. Greenwood, M.D., M.S. Artificial intelligence is currently one of the most commonly discussed topics, but how does it relate to the practice of medicine? According to a recent publication in the Journal of the American Board of Family Medicine, “AI has the potential to fundamentally change th…

1
Mutational and transcriptional landscape of pediatric BCP lymphoblastic lymphoma; the role of platelet-derived TGF-1 in immune thrombocytopenia; phase 3 trial of mavorixafor in WHIM syndrome 23:25

2M ago23:25

23:25

In this week's episode we’ll discuss the mutational and transcriptional landscape of pediatric BCP lymphoblastic leukemia; learn more about the role of platelet-derived TGF-β1 in immune thrombocytopenia; and discuss the findings from a phase 3 trial of mavorixafor in WHIM syndrome. Featured Articles: Mutational and transcriptional landscape of pedi…

1
Management of Varicose Veins 27:20

2M ago27:20

27:20

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Newton B. Neidert, M.D. Varicose veins are quite common and for most, they’re a minor nuisance. However, for some individuals, they have the potential to be much more than a cosmetic health problem. They can lead to a variety of symptoms including skin discoloration, discomfort, extremity swelling and…

1
GM-CSF coordinates shelter in the cytokine storm; Interleukin-1 as a therapeutic target in TTP; CAR T-cell outcomes across race and ethnicity in LBCL 19:57

3M ago19:57

19:57

In this week's episode we'll discuss new insights on the role of GM-CSF in establishing immune memory. The authors propose that the coordination of opposing immune memory programs, driven by GM-CSF, may be essential to efficient, yet controlled, innate immune responses. After that: Interleukin-1 inhibition in TTP. Researchers explore the potential …

1
Review Series on Oncogenic Signaling and Immune Evasion in Hematologic Malignancies 15:41

3M ago15:41

15:41

Introduced by Associate Editor Robert Zeiser, this Review Series focuses on the problem of immune escape by acute myeloid leukemia (AML). The series opens with a review of how AML escapes T-cell–driven elimination and then focuses on how p53 function impinges on AML recognition by immune cells. The series finishes with a summary of new approaches t…

1
Healthcare of the Transgender Patient 24:56

3M ago24:56

24:56

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Natalie C. Erbs, M.D. There is abundant research that indicates there are healthcare inequities experienced by transgender individuals. Transgender patients have the same basic health care needs as any patient. However, in addition, they might also have gender-related healthcare needs and concerns. It…

1
Reassessing the CLL prognostic index; ADAMTS13 conformation and risk of relapse in immune-mediated TTP; haploidentical bone marrow transplant in sickle cell disease 23:39

3M ago23:39

23:39

In this week's episode we’ll discuss the prognostic value of the Chronic Lymphocytic Leukemia International Prognostic Index in the era of targeted therapies, learn how peak ADAMTS13 activity can be used to assess ADAMTS13 conformation and risk of relapse in immune-mediated thrombotic thrombocytopenic purpura, and discuss the findings from a phase …

1
RISE FOR EQUITY Podcast | Pain Points: Strategies to Address Bias in Pain Management 41:36

3M ago41:36

41:36

Brought to you by: Mayo Clinic Talks Podcast HOST: Nicole Nfonoyim-Hara GUESTS: Catherine W. Njathi-Ori, M.D. and Natalie H. Strand, M.D. “On a scale of 1 to 10, what's your pain?” If you’ve just broken a bone or are seeking treatment for endomitosis, it’s likely the first question you’ll be asked. But what if your pain is dismissed or minimized du…

1
A biomarker for disease severity in Wiskott-Aldrich Syndrome; loss of Dnmt3a confers resistance to IFNα; unrelated donor selection in HSCT with PTCy 19:16

3M ago19:16

19:16

In this week's episode we'll discuss assessing risk profile in Wiskott-Aldrich Syndrome, or WAS. Then, we'll learn about how the loss of DNMT3A confers resistance to interferon-alpha in hematopoietic stem cells carrying the JAK2-V617F mutation. Finally, we'll explore unrelated donor selection for AML patients undergoing hematopoietic stem cell tran…

1
Handle with Care to Giving Bad News 26:19

3M ago26:19

26:19

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Amanda K. Lorenz, M.D. Giving our patients bad or unexpected news is one of the most difficult, but also one of the most important responsibilities we have as health care clinicians. This is when our patients need us the most and we need to do this with compassion and empathy. This is best done face t…

1
Nilotinib with or without cytarabine for Philadelphia-positive AML; thrombosis risk in Factor V Leiden and Prothrombin G20210A; ctDNA improves prognostic prediction in relapsed/refractory multiple myeloma ... 23:05

3M ago23:05

23:05

In this week's episode we’ll discuss the safety and efficacy of nilotinib with or without cytarabine in Philadelphia-positive acute lymphoblastic leukemia; learn more about thrombosis risk in double heterozygous carriers of Factor V Leiden and prothrombin G20210A and discuss the utility of circulating cell-free tumor DNA in prognostic prediction in…

1
Infertility 20:11

3M ago20:11

20:11

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Ali J. Ainsworth, M.D. A successful pregnancy is a complicated process. It involves a combination of precise timing as well as anatomic and physiologic conditions which need to be intact and functioning normally. When pregnancy is unable to be achieved, it can be due to a problem in the female, the ma…

1
Hemophilia prophylaxis with fitusiran vs BPA/CFC; germline NBN variants in pediatric B-ALL; Histone demethylation and cell-intrinsic immune response in AML 18:59

4M ago18:59

18:59

In this week's episode we'll learn about fitusiran prophylaxis in patients with hemophilia A or B, with or without inhibitors. Next we'll hear about new findings that heterozygous germline variants in the NBN gene that are linked to increased risk of B-cell acute lymphoblastic leukemia in children. Finally, we'll explore new insights on the histone…

1
Update in Immunizations 2024 28:51

4M ago28:51

28:51

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Robert M. Jacobson, M.D. Immunizations are one of the greatest success stories in modern medicine and it’s estimated that they’ve saved more lives and prevented more disabilities than any other medical intervention. They’re probably responsible, more than any other medical advance in contributing to o…

1
Nutrition and Metabolic Disease 22:42

4M ago22:42

22:42

This episode focuses on important issues related to nutritional assessment and support in surgical patients. Host Rick Greene, MD, FACS, talks to Melissa Coleman, MD, and Joseph Rappold, MD, FACS, about nutritional assessment of critically ill patients, the role of nutrition in the management of a patient with esophageal cancer who is undergoing ne…

1
Effects of voxelotor on cerebral blood flow in pediatric sickle cell disease; thrombosis in Vexas syndrome; response to tyrosine kinase inhibitors in ABL-class acute lymphoblastic leukemia 22:26

4M ago22:26

22:26

In this week's episode we’ll discuss the effects of voxelotor on cerebral blood flow in pediatric sickle cell disease, learn more about venous and arterial thrombosis in patients with Vexas syndrome, and discuss differential sensitivity to tyrosine kinase inhibitors in ABL-class acute lymphoblastic leukemia. Featured Articles: The influence of voxe…

1
RISE FOR EQUITY Podcast | Demystifying Equity: Navigating the Intersection of AI and Healthcare 41:44

4M ago41:44

41:44

Brought to you by: Mayo Clinic Talks Podcast Host: Nicole Nfonoyim-Hara Guests: John Halamka, M.D., M.S., and Sonya Makhni, M.D., M.S., M.B.A. On this episode of the RISE for Equity podcast, Dr. John Halamka and Dr. Sonya Makhni join host Nicole Nfonoyim-Hara to explore the multifaceted realm of Equity in Artificial Intelligence (AI). Delving into …

1
Stamping out high-risk myeloma with D-KRd and tandem transplant; plasmin-cleaved VWF in microthrombosis; SCD plasma sensitizes iPSC-derived sensory neurons 19:40

4M ago19:40

19:40

In this week's podcast we'll discuss another step forward in stamping out high-risk myeloma. Then we'll hear about the plasmin-cleaved von Willebrand factor, or VWF, in microthrombosis. Finally we'll hear about new insights into the origins of sickle cell pain. Featured Articles: Daratumumab, carfilzomib, lenalidomide, and dexamethasone with tandem…

1
Inhalation Injuries in First Responders 25:29

4M ago25:29

25:29

Host: Joshua D. Luciew, MPAS, P.A.-C. Guest: Brittany A. Strelow, DMSc, P.A.-C., M.S. Air pollution is a pervasive issue that surrounds us every day, with varying degrees of severity depending on our environment. As we go about our daily lives, we unknowingly inhale harmful substances that are present in the air. But what happens when this exposure…

1
Allogeneic transplant in first remission for post-induction molecular MRD; circulating HSPCs actively participate in human hematopoiesis; let-7 miRNAs repress HIC2 to regulate BCL11A transcription and ... 21:44

4M ago21:44

21:44

In this week's episode we’ll discuss the utility of MRD in identifying patients with NPM1 AML who benefit from allogeneic transplant in first remission, learn more about the contribution of circulating hematopoietic stem/progenitor cell subsets to human hematopoietic hemostasis, and discuss the role of Let-7 miRNAs in regulation of BCL11A transcrip…

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Venous Disease Podcasts

Podcasts, die es wert sind, gehört zu werden

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