Player FM - Internet Radio Done Right
0-10 subscribers
Checked 1M ago
Vor drei Jahren hinzugefügt
Inhalt bereitgestellt von The Radcliffe Cardiology Podcast. Alle Podcast-Inhalte, einschließlich Episoden, Grafiken und Podcast-Beschreibungen, werden direkt von The Radcliffe Cardiology Podcast oder seinem Podcast-Plattformpartner hochgeladen und bereitgestellt. Wenn Sie glauben, dass jemand Ihr urheberrechtlich geschütztes Werk ohne Ihre Erlaubnis nutzt, können Sie dem hier beschriebenen Verfahren folgen https://de.player.fm/legal.
Player FM - Podcast-App
Gehen Sie mit der App Player FM offline!
Gehen Sie mit der App Player FM offline!
Targeting Inflammation in Atherosclerosis: Therapeutic Targets and Mode of Action
Manage episode 328572038 series 2990303
Inhalt bereitgestellt von The Radcliffe Cardiology Podcast. Alle Podcast-Inhalte, einschließlich Episoden, Grafiken und Podcast-Beschreibungen, werden direkt von The Radcliffe Cardiology Podcast oder seinem Podcast-Plattformpartner hochgeladen und bereitgestellt. Wenn Sie glauben, dass jemand Ihr urheberrechtlich geschütztes Werk ohne Ihre Erlaubnis nutzt, können Sie dem hier beschriebenen Verfahren folgen https://de.player.fm/legal.
Prof Juan Carlos Kaski (St George’s University of London, UK) alongside Dr Peter Libby (Brigham and Women’s Hospital, Boston, US) provide us with a short and concise discussion regarding Therapeutic Targets and Mode of Action. Supported by an unrestricted educational grant from NOVO NORDISK A/S.
…
continue reading
46 Episoden
Manage episode 328572038 series 2990303
Inhalt bereitgestellt von The Radcliffe Cardiology Podcast. Alle Podcast-Inhalte, einschließlich Episoden, Grafiken und Podcast-Beschreibungen, werden direkt von The Radcliffe Cardiology Podcast oder seinem Podcast-Plattformpartner hochgeladen und bereitgestellt. Wenn Sie glauben, dass jemand Ihr urheberrechtlich geschütztes Werk ohne Ihre Erlaubnis nutzt, können Sie dem hier beschriebenen Verfahren folgen https://de.player.fm/legal.
Prof Juan Carlos Kaski (St George’s University of London, UK) alongside Dr Peter Libby (Brigham and Women’s Hospital, Boston, US) provide us with a short and concise discussion regarding Therapeutic Targets and Mode of Action. Supported by an unrestricted educational grant from NOVO NORDISK A/S.
…
continue reading
46 Episoden
Alle Folgen
×This episode examines the multidisciplinary team (MDT) in HCM, exploring its ideal structure, function, and real-world challenges. Prof Juan Pablo Kaski is joined by Dr Elena Biagini and Dr Jodie Ingles to share insights from their work on the 2023 ESC guidelines and MDT care.
In this exclusive episode of the "Innovations in Cardiology" podcast series, host Dr Dipti Itchhaporia, past president of the American College of Cardiology, delves into the latest advancements in cardiovascular health. She is joined by Dr Valentin Fuster, a pioneer in the field, who shares invaluable insights into the impact of biological ageing, the connection between the heart and brain, and the role of artificial intelligence in healthcare. Dr Fuster challenges the traditional focus on chronological age, highlighting the significance of biological age as a more accurate predictor of cardiovascular risk. Together, he and Dr Itchhaporia explore innovative ways to measure biological age and discuss the factors that influence it. The conversation then shifts to the importance of early intervention in cardiovascular disease, with Dr Fuster advocating for screening in younger individuals. They also discuss the transformative potential of polypills in preventing and treating heart disease, weighing the benefits against challenges such as adherence and cost-effectiveness. As the episode wraps up, Dr Fuster offers his predictions for the future of cardiovascular care and shares valuable advice for those just beginning their careers in the field. If you have any questions or suggestions for topics to cover on the Radcliffe Podcast, please email managingeditor@ecrjournal.com.…
Join interventional cardiologists, Prof Nicolas Van Mieghem and Dr Joost Daemen from the Thoraxcenter as they unpack the most impactful late-breaking clinical trials and science data from this year's Transcatheter Cardiovascular Therapeutics Conference. Dive into this practical and engaging discussion and learn more about the latest data for practice and for research. Trials covered in detail include: ECLIPSE (00:49 - 05:55) FAVOR III (05:55 - 10:30) FLASH (10:30 - 12:54) DCB BIFURCATION (12:54 - 15:17) EARLY TAVR (15:17 - 21:14) EVOLVED (21:14 - 24:07) TAVR-UNLOAD (24:07 - 28:57) PEERLESS (28:57 - 31:14) CLEAR IE (31:14 - 33:29) TRISCEND II (33:29 - 36:36) ACCESS TAVI (36:36 - 40:05) ALIGN AR (40:05 - 41:49) COSTAR RCT (41:49 - 43:36) ACURATE IDE (43:36 - 46:42) CLEAR SYNERGY(46:42 - 48:41) This is an independent interview produced by Radcliffe Cardiology.…
In this episode of the "Innovations in Cardiology" series, host Dr Dipti Itchhaporia (Hoag Heart and Vascular Institute, Newport Beach, CA, US) is joined by Dr Alexander Van Rosendael (Leiden University Medical Center, Leiden, NL) to discuss the findings from the CONFIRM2 trial. Conducted from up to 50 international clinical CCTA sites with 35,000 patients, CONFIRM2 aims to improve comprehensive quantification of coronary computed tomography angiography findings using an artificial intelligence algorithm that will enable an accurate quantification of coronary artery disease, including total coronary plaque volume and low attenuation plaque volume. Findings showed that AI-guided quantative computational tomography quantification of coronary CTA lumen diameter stenosis and the noncalcified plaque volume were most predictive of MACE and added discriminative accuracy to the Diamond and Forrester predictive model. These atherosclerotic profiles as assessed by AI-QCT could guide the tailoring of anti atherosclerotic therapies or coronary interventional procedures to reduce the instance of cardiac events. If you have any questions or suggestions for topics to cover on the Radcliffe Podcast, please email managingeditor@ecrjournal.com.…
Explore the cardiovascular breakthroughs shaping AHA 2024! Join renowned experts Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcenter, Erasmus MC, Rotterdam, NL) as they preview the most impactful late-breaking studies poised to make waves at this year’s AHA Conference. Dive into their expert analysis and gain key insights into the studies that are set to drive the future of cardiovascular care. Trials discussed in detail include: CLEAR-SYNERGY (01:01 - 03:45) SELECT (03:45 - 04:47) SUMMIT (04:47 - 08:28) YELLOW III (08:28 - 11:05) AMULET IDE (11:05 - 12:25) VALOR-HCM (12:25 - 13:39) Stay tuned for Radcliffe Cardiology's in-depth coverage of these and other pivotal trials from AHA Conference 2024.…
In this episode of the "Innovations in Cardiology" series, host Dr. Dipti Itchhaporia, former president of the ACC, is joined by Dr. C. Michael Gibson, CEO of the Baim Institute for Research, for an insightful discussion on the latest advancements and future directions in cardiovascular innovation for 2024. Dr. Itchhaporia and Dr. Gibson explore strategies to enhance efficiency in cardiovascular research, with a focus on direct-to-patient trials. They delve into how this approach can be optimized to better target patients and improve outcomes. Dr. Gibson shares details about a groundbreaking platform being developed to support long-term follow-up studies, enabling patient monitoring for up to 20 years through persistent follow-up alerts. The conversation also touches on key findings from the Apple Heart Study, particularly in relation to atrial fibrillation detection via the Apple Watch, and the differences in compliance rates between older and younger patients. Additionally, they discuss the upcoming results of the Heartline Study, which focuses on patients aged 65 and older. Looking ahead, Dr. Itchhaporia and Dr. Gibson reflect on the future of cardiovascular care, including the potential for personalized care plans tailored to each patient. They consider the timeline for integrating this approach into clinical practice, potential barriers to implementation, and the significant opportunities it presents for improving patient outcomes. If you have any questions or suggestions for topics to cover on the Radcliffe Podcast, please email managingeditor@ecrjournal.com.…
Host, Dr Dipti Itchhaporia (Hoag Heart and Vascular Institute, Newport Beach, CA, US) is joined by PI, Dr Derek Chew (Monash Heart and Victorian Heart Institute, AU) to discuss the findings from the RAPIDxAI trial, which aims to improve the assessment of suspected cardiac chest pain in emergency departments (ED) using a machine-learning algorithm that will interpret high-sensitivity troponin test results, assisting the diagnosis of myocardial infarction (MI) and other myocardial injuries. Conducted across 12 hospitals with 9600 patients, RAPIDxAI compares AI-supported decision-making to standard of care. Investigators found that the availability of AI-based decision making tools guiding diagnostic and prognostic evaluation of high-sensitivity troponin T did not impact clinical care to improve cardiovascular outcomes. There was no increased risk using the algorithms observed in the trial, demonstrating the safety of the algorithm. Dr Itchhaporia and Dr Chew discuss the trust levels of cardiologists in implementing AI algorithms into clinical practice, and cost-effective methods of validating AI, as well as the lessons learnt from the trial. If you have any questions or suggestions for topics to cover on the Radcliffe Podcast, please email managingeditor@ecrjournal.com.…
In this episode of the "Innovations in Cardiology" series, host Dr Dipti Itchhaporia welcomes two leading experts in artificial intelligence in cardiology: Dr David Ouyang from Cedars-Sinai Medical Center in Los Angeles, and Dr Francisco Lopez-Jiminez from the Mayo Clinic in Rochester, MN. Together, they explore the role of artificial intelligence in cardiology, from diagnostics to personalized treatment strategies. Dr. Lopez-Jiminez shares insights from the AI-ECG study, delving into its clinical reception and the potential for scaling these findings across various healthcare settings. Dr. Ouyang addresses the challenges of integrating AI into clinical practice, highlighting the areas where rapid advancements are occurring. Both experts offer valuable advice to clinicians who would like to stay abreast of AI trends in healthcare, and engage in debate on whether AI will ultimately revolutionize clinical care, including the timelines for these anticipated changes. If you have any questions or suggestions for topics to cover on the Radcliffe Podcast, please email managingeditor@ecrjournal.com.…
What's hot at ESC Congress 2024? Join us for a comprehensive analysis of the most impactful hot line trials presented at the European Society of Cardiology (ESC) Congress 2024. In the latest episode of the View from the Thoraxcenter, Prof Nicolas van Mieghem and Dr Joost Daemen (Thoraxcenter at Erasmus MC, NL) provides an overview of the new findings and their implications for clinical practice. What should we consider when interpreting hotline data from ESC 24? How will these trials impact future research? What questions should we ask before applying the new data to clinical practice? Trials in detail covered: 00:37 RESHAPE-HF2 06:11 MATTERHORN 11:01 Tri.fr 14:43 SWEDEGRAFT 17:46 OCCUPI 22:59 REC-CAGEFREE I 28:10 SENIOR-RITA 32:58 EARTH-STEMI 35:23 POPular PAUSE TAVI 38:31 NOTION-3 44:32 RHEIA Support: This is an independent interview produced by Radcliffe Cardiology.…
This episode features a comparative summary of international guidelines, highlighting key differences and assessing the adequacy of current recommendations. The discussion also identifies gaps in existing clinical evidence, providing insights into what is currently missing in HCM research.
In this episode, Prof Juan Pablo Kaski is joined by Dr Carolyn Ho, join them in this 20-minute discussion on essential management topics, including phenotyping, triaging, symptomatic care, and transplant considerations.
In this episode, Prof Juan Pablo Kaski is joined by Dr Jodie Ingles and Dr Elena Biagini to discuss long-term management, expectations in cardiology, community care and family genetic screening. Tune in for expert insights on supporting patients and their families.
What's hot at EuroPCR 2024? Join interventional experts, Prof Nicolas Van Mieghem and Dr Joost Daemen from Erasmus MC's Thoraxcenter for an insightful preview of the late-breaking science data to look out for at the 2024 EuroPCR meeting. What is the potential impact of the new data on practice? What details should we look out for? What is the context of the EuroPCR trials? Trials covered included: 00:46 - CAREER 02:03 - Angiography-based Radial Wall Strain in Predicting Non-Culprit Vessel Failure 04:05 - DOCTORS-LM 07:41 - TCW 09:35 - SOLVE-TAVI 12:27 - NOTION-2 14:41 - LANDMARK 16:36 - AltaValve 17:53 - LuxValvePlus 19:12 - CALIPSO 21:44 - ROTA-ISR 23:57 - ROLLERCOASTR 25:20 - Balloon Angioplasty Vs Shockwave Intravascular Lithotripsy 25:29 - OCT Vs IVUS…
In the first episode, Prof Juan Pablo Kaski and Prof Ruxandra Jurcut discuss the essentials of establishing an HCM Clinic, covering its objectives, logistical aspects, systemic challenges, and operational strategies, including referral practices and collaboration with specialist centres.
Unpack ACC.24's Top Trials with View from the Thoraxcenter! Join Prof Nicolas Van Mieghem and Dr Joost Daemen from Erasmus MC, Rotterdam for a deep dive into the late-breaking data presented at ACC.24. In this thought-provoking ACC 2024 wrap-up, delve into the nuances of the most impactful trials, gaining insights into their implications for current practice and future research directions. 00:29 - Ultimate DAPT 02:49 - IVUS-ACS 04:22 - RELIEVE-HF 08:00 - ORBITA-COSMIC 11:12 - EMPACT-MI 14:36 - REDUCE-AMI 17:51 - DEDICATE-DZHK6 22:32 - SMART 26:26 - PREVENT 29:08 - FULL REVASC 33:43 - DanGer Shock 39:44 - TARGET BP I…
Willkommen auf Player FM!
Player FM scannt gerade das Web nach Podcasts mit hoher Qualität, die du genießen kannst. Es ist die beste Podcast-App und funktioniert auf Android, iPhone und im Web. Melde dich an, um Abos geräteübergreifend zu synchronisieren.