Journal Club: Vargas et al - Intracellular 5-HT2ARs?

Psychedelic Brain Science

Join Zarmeen and Alaina this week as they discuss a recent research article challenging the currently accepted mechanism of psychedelic action. This paper titled "Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors" by Vargas and colleagues uses several techniques in neuroscience and chemistry to understand just how psychedelic tryptamines, but not serotonin itself, is causing plasticity changes in the frontal cortex. The gals will walk listeners through the paper and talk about some positive aspects and some critiques. All content published by YBOS is solely the opinions of the authors and does not reflect the opinions of any parties affiliated with the authors or any additional third parties.