Beste Patio11 Podcasts (2025)

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Getting better at LLMs, with Zvi Mowshowitz 51:50

vor 2 Tagen51:50

51:50

In this episode, Patrick McKenzie (patio11) recorded with Zvi Mowshowitz (TheZvi) live at the LessOnline conference. They explore practical strategies for getting better results from large language models. Zvi explains how to customize AI behavior through thoughtful system prompts, while Patrick shares techniques for using LLMs as writing partners …

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Machine learning meets malware, with Caleb Fenton 1:21:16

vor 9 Tagen1:21:16

1:21:16

Patrick McKenzie (patio11) discusses software reversing and AI's transformative impact on cybersecurity with Caleb Fenton, co-founder of Delphos Labs. They explore how LLMs are revolutionizing the traditionally tedious work of analyzing compiled binaries, the nation-state cyber warfare landscape, and how AI is shifting security from reactive to pro…

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How to negotiate your salary package 45:21

vor 16 Tagen45:21

45:21

In this episode, Patrick McKenzie (patio11) revisits his widely-shared negotiation essay, which he notes may be the most impactful thing he's done in his career aside from VaccinateCA. The essay covers the psychology and tactics of salary negotiation, emphasizing that engineers have turned being bad at negotiation into a "perverse badge of virtue" …

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The capitalist's guide to podcasting, with Ross Rheingans-Yoo 1:03:27

vor 23 Tagen1:03:27

1:03:27

In this episode, Patrick McKenzie (patio11) and returning guest Ross Rheingans-Yoo discuss the strategic advantages of starting a podcast, particularly for professionals seeking to build trust, expand their networks, and support fundraising efforts. They explore the nuts and bolts of podcast production models, recording logistics, transcript creati…

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Killing viruses with light, with Jacob Swett 1:01:43

vor 30 Tagen1:01:43

1:01:43

In this episode, Patrick McKenzie (patio11) is joined by Jacob Swett of Blueprint Biosecurity to discuss far UVC technology - a specialized wavelength of UV light that kills airborne pathogens while remaining safe for humans. Jacob explains how widespread deployment of this technology in schools, hospitals, and public spaces could dramatically redu…

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Life insurance and your money, with Zac Townsend 1:20:53

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vor etwa einem Jahr1:20:53

1:20:53

In this episode, Patrick McKenzie (patio11) is joined by Zac Townsend, a serial founder and CEO of Meanwhile, a fully regulated life insurance company operating in Bitcoin. They explore the differences between life and property insurance, explain why term life is essential financial protection everyone should consider, and dive into the tax benefit…

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Fixing government technology, with Mikey Dickerson 53:39

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vor etwa einem Jahr53:39

53:39

In this episode, Patrick McKenzie (@patio11) is joined by Mikey Dickerson to discuss the complex realities behind government software projects. Mikey shares insights from leading the healthcare.gov rescue effort and founding the United States Digital Service, explaining how procurement processes create requirements through committee decision-making…

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Understanding and wielding power in local government, with Daniel Golliher 59:35

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vor etwa einem Jahr59:35

59:35

In this episode, Patrick McKenzie (@patio11) is joined by Daniel Golliher, founder of Maximum New York, to discuss the opaque mechanics of political power and how everyday people can effectively engage with government systems. They explore the stark gap between formal political science degrees and how politics actually works, practical tactics for …

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The AI energy bottleneck, with Tim Fist 1:06:05

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vor etwa einem Jahr1:06:05

1:06:05

In this episode, Patrick McKenzie (@patio11) is joined by Tim Fist, Director of Emerging Technologies at the Institute for Progress, to discuss how energy constraints could bottleneck AI development. They explore how AI training clusters will soon require gigawatts of power—equivalent to multiple nuclear plants—with projections showing a single clu…

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Taking stablecoins seriously, with Haseeb Qureshi 1:08:05

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vor etwa einem Jahr1:08:05

1:08:05

In this episode, Patrick McKenzie (@patio11) is joined by Haseeb Qureshi, a managing partner at Dragonfly, a crypto-focused VC fund. They discuss the evolution of stablecoins, three key use cases, and their impact on international finance. Haseeb explains how stablecoins have grown beyond their initial association with crypto trading and illicit ac…

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The past, present, and future of AI, with Stripe 1:33:48

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vor etwa einem Jahr1:33:48

1:33:48

Patrick McKenzie (patio11) is joined by Emily Sands, Head of Information at Stripe, to discuss how they leverage AI to process over $1.4 trillion annually, while navigating the complex web of merchants, banks, and payment rails that facilitate online commerce. Patrick and Emily cover how Stripe’s layered stack of AI combats sophisticated card testi…

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No, poor people aren’t funding your credit card rewards 1:06:47

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vor etwa einem Jahr1:06:47

1:06:47

In this episode, Patrick McKenzie (patio11) challenges a recent Atlantic article claiming that low-income cardholders subsidize credit card rewards through high interest payments. Drawing from his Bits About Money essay Anatomy of a credit card rewards program, Patrick explains that rewards are primarily funded by interchange fees paid by merchants…

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Points, profits, and packed planes, with Gary Leff 1:31:27

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vor etwa einem Jahr1:31:27

1:31:27

Patrick McKenzie (patio11) is joined by Gary Leff, the author of "View from the Wing", to discuss the economic systems behind airlines and loyalty programs. They discuss how airlines manage to stay profitable despite razor-thin margins, the economics of frequent flyer programs, and why these programs often generate more value than the airlines them…

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Tax the dirt, with Lars Doucet & Greg Miller 1:17:07

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vor etwa einem Jahr1:17:07

1:17:07

Patrick McKenzie (patio11) is joined by Lars Doucet and Greg Miller, co-founders who have just launched the Center for Land Economics, to discuss improving property taxation in the US. They explore how shifting taxes from buildings to land could transform development patterns, why California's property tax caps coincide with its housing crisis, and…

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A tale of two Americas in one $50K cash withdrawal 41:13

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vor etwa einem Jahr41:13

41:13

Patrick McKenzie (patio11) explains the standard procedure for large withdrawals in bank branches, with particular focus on the viral story published in The Cut about a woman who withdrew $50,000 cash from a bank and handed it to scammers. Certain minor details in the article set off a year-long investigation where he identified the exact physical …

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AI, data centers, and power economics, with Azeem Azhar 1:13:53

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vor etwa einem Jahr1:13:53

1:13:53

Patrick McKenzie (patio11) is joined by Azeem Azhar, writer of the Exponential View newsletter, to discuss the massive data center buildout powering AI and its implications for our energy infrastructure. The conversation covers the physical limitations of modern datacenters, the challenges of electricity generation, the societal ripples from histor…

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You can’t retract the facts 42:03

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vor etwa einem Jahr42:03

42:03

In this episode, Patrick McKenzie (@patio11) responds to a recent request by a crypto unicorn founder / bank CEO to retract his essay Debanking (and debunking?). Come for the note about editorial standards and independence, stay for the diss track. – Full transcript available here: https://www.complexsystemspodcast.com/editorial-standards-and-indep…

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Stablecoins and shenanigans, with Zeke Faux 1:27:03

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vor etwa einem Jahr1:27:03

1:27:03

In this episode, Patrick McKenzie (@patio11) is joined by Zeke Faux, investigative reporter at Bloomberg and author of Number Go Up, to discuss stablecoins and crypto fraud. They dive into Tether's controversial history, the senate’s emerging GENIUS act, and how crypto enables various types of financial crime. The conversation explores how Tether w…

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Power plays: grid economics and engineering, with Travis Dauwalter 1:13:46

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vor etwa einem Jahr1:13:46

1:13:46

Patrick McKenzie (@patio11) is joined by Travis Dauwalter, energy enthusiast (and PhD), to explain the systems we often take for granted behind the US electrical grid. The conversation covers how the grid maintains perfect supply-demand balance in real-time, the challenges of integrating renewable energy sources, and why America actually has three …

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The landmines buried in the fine print of Chicago’s new casino deal 43:23

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vor etwa einem Jahr43:23

43:23

In today’s episode Patrick McKenzie (@patio11) examines a Chicago casino investment, first of its kind within the city limits. Patrick reads from his Bits About Money essay (published January 2025) with additional commentary based on recent developments. The discussion reveals how municipal politics, grievances about national and local economic his…

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The banking crisis, two years later 1:09:48

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vor etwa einem Jahr1:09:48

1:09:48

Patrick McKenzie (@patio11) revisits his March 2023 essay that explained the dynamics of bank runs and system stress during the banking crisis one month prior. With data from a newly released Federal Reserve paper, he analyzes the true scope of the banking stress - including revelations that 22 banks experienced severe deposit outflows, far more th…

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Debanking explained 1:00:43

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vor etwa einem Jahr1:00:43

1:00:43

In this episode, Patrick McKenzie (@patio11) unpacks his 24k word essay Debanking (and Debunking?) originally published on Bits about Money. He discusses the contours of recent debanking claims made by the crypto community, notably Marc Andreessen, Nic Carter, and explains how banking actually works as infrastructure rather than conspiracy. The con…

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Retrospective on 2024, with Sammy Cottrell 1:03:50

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vor etwa einem Jahr1:03:50

1:03:50

In this special episode, Patrick McKenzie (@patio11) and his EA/producer Sammy Cottrell examine the production function behind Complex Systems, from studio logistics to transcript annotation and guest selection. They reflect on their most memorable episodes while discussing the podcast's core mission of making complex systems more legible and ensur…

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Seeing like an outsider, with Yatharth 1:19:31

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vor etwa einem Jahr1:19:31

1:19:31

In this episode, Yatharth (@askyatharth), a graduate student and software engineer, turns the tables to interview Patrick McKenzie (@patio11) about cultural codes, writing, and AI. Patrick shares how his early experiences fighting credit report errors and navigating cross-cultural business environments led to his distinctive approach to understandi…

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The future of pandemic preparedness, with Joshua Morrison 1:12:30

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vor etwa einem Jahr1:12:30

1:12:30

In this episode, Patrick McKenzie (patio11) is joined by Joshua Morrison, the CEO of advocacy non-profit 1Day Sooner. They discuss what worked and what didn't in Operation Warp Speed's unprecedented push to develop COVID-19 vaccines. The conversation then turns to the future of pandemic preparedness, particularly the promising (and underappreciated…

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How we tax property, with Lars Doucet 1:09:36

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vor etwa einem Jahr1:09:36

1:09:36

In this episode, Patrick McKenzie (patio11) and Lars Doucet, the author of Land is a Big Deal, discuss how cities determine your property's value and collect taxes. They explore how assessment offices juggle political pressures, statistical models, and technological tools while trying to maintain equity across millions of properties. They also cove…

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Fraud levels are a policy choice 49:21

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vor etwa einem Jahr49:21

49:21

In this episode, Patrick McKenzie (patio11) offers a reading of his viral essay, "The optimal amount of fraud is non-zero" with extensive live commentary. Patrick examines payment systems, benefits programs, and pandemic-era policies, to uncover how businesses and governments often intentionally accept some level of fraud as a cost of doing busines…

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AI, poker, and mind games, with Max Chiswick 55:00

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vor etwa einem Jahr55:00

55:00

Patrick McKenzie (patio11) is joined by Max Chiswick, a former professional poker player turned AI educator, to explore how poker intersects with decision making. They discuss how the online poker boom created unprecedented opportunities to study decision-making at scale and how computational advances have transformed both the game's theory and pra…

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Boom, busts, and long term progress with Byrne Hobart 1:42:59

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vor etwa einem Jahr1:42:59

1:42:59

By popular demand, Patrick McKenzie (patio11) is joined by Byrne Hobart for a 3rd conversation to discuss Byrne’s book "Boom: Bubbles and the End of Stagnation." They explore how periods of irrational market enthusiasm often create lasting value despite their painful endings. Using examples from the 1990s fiber optic boom that enabled modern stream…

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How money moves, with Erik Torenberg 37:21

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vor etwa einem Jahr37:21

37:21

In this episode, Patrick McKenzie (patio11) is joined by Erik Torenberg, the founder of Turpentine, to discuss the fundamentals of money movement and banking systems. Patrick breaks down how banks facilitate transfers through correspondent accounts and clearinghouses, explaining the evolution from physical check movement to digitization. They cover…

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From molecule to medicine, with Ross Rheingans-Yoo 1:27:14

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vor etwa einem Jahr1:27:14

1:27:14

In this episode, Patrick McKenzie (patio11) is joined by Ross Rheingans-Yoo to discuss drug development and clinical trials. Ross breaks down how drugs progress from academic research through FDA approval, the challenging economics, and the many systemic inefficiencies in the current approval process. Patrick and Ross discuss historical cases like …

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Picking Uncle Sam's pocket, with Jetson Leder-Luis 1:18:10

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vor etwa einem Jahr1:18:10

1:18:10

In this episode, Patrick McKenzie (patio11) is joined by economist and fraud researcher Professor Jetson Luis-Leder to examine the systemic issues underlying government program fraud. Jetson and Patrick discuss healthcare fraud cases, including hospice eligibility manipulation and ambulance transport schemes, and other fraud practices against unemp…

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How real estate investing works with Moses Kagan 1:28:30

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vor etwa einem Jahr1:28:30

1:28:30

In this episode, Patrick McKenzie (patio11) is joined by Moses Kagan, co-founder of Adaptive Realty, ReSeed, and Reconvene. Their deep dive into real estate investing and property management covers the different classes of apartment buildings, the challenges of property management, and the complexities of financing structures in the industry. They …

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Telling the tech story 58:34

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vor etwa einem Jahr58:34

58:34

In this episode, Patrick McKenzie (patio11) and Erik Torenberg, investor and the media entrepreneur behind Turpentine, explore the evolving relationship between tech journalism and the industry it covers. They discuss how fictional portrayals of industries greatly inform how jobseekers understand those industries, and how the industries understand …

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The hundred-year-old telegram worth $5 million, with Jim McKenzie 1:52:36

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vor etwa einem Jahr1:52:36

1:52:36

Patrick McKenzie (patio11) is joined by his father, Jim McKenzie, for an intimate and in depth exploration of commercial real estate development. They unravel the complex web of relationships, regulations, and often absurd situations that shape our built environment. From the intricacies of curb cuts and driveway permits to the art of navigating lo…

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Bits, Bytes, and Burgers with Byrne Hobart 1:26:13

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vor etwa einem Jahr1:26:13

1:26:13

Patrick McKenzie (patio11) is joined again by Byrne Hobart, writer of The Diff, for a follow up conversation about “whales” – and so much more – across the gaming, aviation, software, hospitality and fast food industries. Patrick and Byrne also discuss their writing process, knowledge management, and how they use AI tools. – Full transcript availab…

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Decisions Nobody Made, policy edition, with Dave Guarino 1:22:26

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vor etwa einem Jahr1:22:26

1:22:26

In this episode of Complex Systems, Patrick McKenzie (aka @Patio11) is joined by Dave Guarino, a software engineer and policy wonk. They explore the complexities and challenges of public programs, focusing on SNAP aka CalFresh in California, where Dave was the founding engineer and then director. They discuss how society’s complex preferences becom…

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True Crime, banking edition 53:12

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vor etwa einem Jahr53:12

53:12

In this episode of Complex System, the tables are turned and media entrepreneur/investor Erik Torenberg interviews Patrick McKenzie (patio11) about the intricacies of the financial system, focusing on banking, money laundering, and regulatory compliance. They discuss several of Patrick’s essays from Bits About Money. Patrick discusses the three sta…

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That time we accidentally created national healthcare infrastructure, with Dave Kasten 1:36:06

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vor etwa einem Jahr1:36:06

1:36:06

In this episode, Patrick McKenzie (patio11) is joined by Dave Kasten, to discuss their experiences building VaccinateCA, a charitable effort that collected, collated, and distributed vaccine distribution information during the COVID-19 pandemic. (If you Googled for the vaccine, the search results likely came from VaccinateCA’s data.) They cover the…

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The mad science of drilling the earth with Austin Vernon 1:11:23

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vor etwa einem Jahr1:11:23

1:11:23

Patrick McKenzie (patio11) is joined by Austin Vernon, a petroleum engineer, to discuss the technology and economics of fracking. Austin explains the evolution of drilling technology, the financial ecosystem supporting the oil industry – including the unique "doctor and lawyer money" funding model – and the complex interplay of mineral rights laws …

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Balancing control and chaos: cybernetics, fraud, and modern organizations with Dan Davies 1:23:56

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vor etwa einem Jahr1:23:56

1:23:56

In this episode, Patrick McKenzie (patio11) is joined by Dan Davies, author of Lying for Money, and The Unaccountability Machine. They discuss how cybernetics–the study of control and communication in complex systems–applies to modern organizations and decision-making. Dan and Patrick discuss how organizations change as they grow, financial fraud a…

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Energy economics and rocket science with Casey Handmer 1:25:18

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vor etwa einem Jahr1:25:18

1:25:18

Patrick McKenzie (patio11) is joined by Casey Handmer, rocket scientist turned CEO of Terraform Industries. Casey discusses the rapid advancements in solar power, the bureaucratic challenges of NASA, the incomprehensible success of SpaceX, and the evolving energy landscape. Casey touches on his experiences at JPL revealing how the organization’s fe…

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Bet on it: Zvi Mowshowitz on professional gambling, trading, and AI futures 1:26:22

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vor etwa einem Jahr1:26:22

1:26:22

In this episode, Patrick McKenzie (patio11) is joined by Zvi Mowshowitz (TheZvi) to discuss his wide-ranging career as a professional Magic: The Gathering player, sports gambler, equities trader, public intellectual on the covid-19 epidemic, and AI-focused journalist. They go into depth on how trading happens in less formal markets with lessons tha…

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Betting on the future via prediction markets, with Stephen Grugett of Manifold 51:57

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vor etwa einem Jahr51:57

51:57

In this episode, Patrick McKenzie (patio11) is joined by Stephen Grugett, a co-founder of Manifold, to discuss prediction markets. They cover how prediction markets work, their efficiency in aggregating information, and why they serve as a minority report against prevailing narratives. They cover past controversies, potential risks, and the philoso…

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Reporting on tech with Kelsey Piper 1:06:40

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vor etwa einem Jahr1:06:40

1:06:40

Patrick McKenzie (patio11) is joined by Kelsey Piper, a journalist for Vox’s Future Perfect. Kelsey recently reported on equity irregularities at OpenAI in May of 2024, leading to an improvement of their policies in this area. We discuss the social function of equity in the technology industry, why the tech industry and reporters have had a frosty …

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Writing the first draft of financial history with Byrne Hobart 50:45

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vor etwa einem Jahr50:45

50:45

Patrick McKenzie (patio11) is joined by Byrne Hobart to discuss Byrne’s vantage point as writer of The Diff, a tech and finance newsletter. Byrne explains the toxicity of the 30-year mortgage, the dynamics of the finance newsletter ecosystem, how rationalist epistemics can be applied to hedge funds, and the joy of learning about an industry from sc…

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How the Smart Money teaches trading with Ricki Heicklen 1:40:15

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vor etwa einem Jahr1:40:15

1:40:15

Patrick McKenzie (patio11) and Ricki Heicklen discuss Ricki’s innovative approaches to teaching trading. Trading is traditionally taught only by practitioners, to practitioners. The curricula that trading firms use are not published externally, to avoid empowering competitors. Ricki explains how she teaches trade mechanics, how markets and traders …

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Patio11 Podcasts

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