Squid Game is back—and this time, the knives are out. In the thrilling Season 3 premiere, Player 456 is spiraling and a brutal round of hide-and-seek forces players to kill or be killed. Hosts Phil Yu and Kiera Please break down Gi-hun’s descent into vengeance, Guard 011’s daring betrayal of the Game, and the shocking moment players are forced to choose between murdering their friends… or dying. Then, Carlos Juico and Gavin Ruta from the Jumpers Jump podcast join us to unpack their wild theories for the season. Plus, Phil and Kiera face off in a high-stakes round of “Hot Sweet Potato.” SPOILER ALERT! Make sure you watch Squid Game Season 3 Episode 1 before listening on. Play one last time. IG - @SquidGameNetflix X (f.k.a. Twitter) - @SquidGame Check out more from Phil Yu @angryasianman , Kiera Please @kieraplease and the Jumpers Jump podcast Listen to more from Netflix Podcasts . Squid Game: The Official Podcast is produced by Netflix and The Mash-Up Americans.…
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The Michael J. Fox Foundation Parkinson's Podcast
The Michael J. Fox Foundation for Parkinson’s Research
Subscribe for coverage and analysis of current neurology/brain research, patient and caregiver profiles, drug development strategy, pioneering nonprofit management and other topics of interest in a wide-ranging series of conversations that include the voices of those affected by Parkinson's as well as clinicians.
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Kansas City update
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What Imaging Tech Can Reveal About Parkinson's
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36:06Advances in imaging technology offer researchers a window into how Parkinson’s disease affects the brain, which could reshape how the disease is diagnosed and treated. In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, in its award-winning Parkinson’s Science POV series, David Kumbroch, senior science writer at MJFF, lead a conve…
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Building Your Best Parkinson’s Care Team (Webinar Audio)
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54:27Having a network of health care professionals, loved ones and community members as part of a care team has shown to improve the quality of life for those living with Parkinson’s disease (PD) and their loved ones. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss how to make the most of your appointments, fi…
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Understanding the Experience of LGBTQ+ People Living with Parkinson’s Disease
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45:03Life with Parkinson’s disease (PD) is shaped by myriad factors, including sexual orientation and gender identity that shape access to care, lifestyle decisions and more. In this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast, our expert panel shares their personal stories and discusses the ongoing research into the health concerns a…
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Changing the Narrative: Destigmatizing Parkinson’s Disease (Webinar Audio)
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53:07The beliefs and perceptions that friends, family, employers and even strangers hold about Parkinson’s disease (PD) shape the experience of living with the disease. Facing misperceptions and stigma can cause isolation and worsen symptoms. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts have a candid and compassion…
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How Engagement Helps Your Journey with Parkinson's
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41:02There are so many ways to get involved with Parkinson’s disease, from community building to advocacy, research participation to fundraising. Taking that first step toward involvement can be daunting, but many people say it’s a critical part of living well with the disease. In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, member…
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How Do You Feel with Parkinson’s? A Special Edition Webinar on Emotions (Webinar Audio)
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1:17:31Life with Parkinson’s comes with a vast range of emotions, wherever you are in your disease journey. Shock, grief, optimism, fear, denial, hope, humor and more can all be a part of the emotional landscape for people living with the disease and their loved ones. Tune into audio from this special edition Third Thursdays Webinar to listen to our panel…
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Sniff Test: Surprising New Learnings About Smell Loss and Parkinson’s (Webinar Audio)
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56:15Smell loss can be among the earliest signs of Parkinson’s disease (PD) and other neurodegenerative diseases, signaling changes in the brain years before other symptoms are noticeable. Because of the link between smell and brain health, researchers are very interested in understanding more about how people with smell loss go on to either develop a d…
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What Parkinson’s Genetics Mean for Personal Experience and Research
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38:45You could take any two humans on earth and their genetic code will be roughly 99 percent the same — it’s the small differences in code that lead to different experiences and outcomes, including the risk of developing diseases like Parkinson’s. Scientists are learning more about which genetic changes are linked to Parkinson’s disease, revealing impo…
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The Path to a Parkinson’s Drug Approval (Webinar Audio)
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58:08With three new Parkinson’s treatments approved in the last year, there are more options than ever before for people living with the disease. Tune into audio from this Third Thursdays Webinar to hear movement disorder specialists, research experts and a person living with Parkinson’s answer community questions about the new treatments available, exp…
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What’s in Your Parkinson’s Medicine Cabinet (Ask the MD Podcast)
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12:58Movement disorder specialist, lifestyle medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, MD, DipABLM, shares tips on medication management for people at every stage of the disease journey. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Founda…
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Managing the Hidden Symptoms: Mood and Motivation Changes in Parkinson’s (Webinar Audio)
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55:23If depression, anxiety or apathy occur as part of a Parkinson’s journey, it can be easy to feel alone, isolated or unsure of what might bring relief. But there are ways to manage these symptoms. Tune into audio from this Third Thursdays Webinar to hear people living with Parkinson’s share their stories of coping with mood changes as well as a movem…
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Your Top Questions on Parkinson’s and Exercise Answered (Ask the MD Podcast)
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27:03Movement disorder specialist, lifestyle medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, MD, DipABLM, answers community questions on Parkinson’s and exercise with physical therapist and rehab scientist Cristina Colón-Semenza, PhD. Listen to the audio or watch the video. Like our podcasts? Please consider leaving a rating or revi…
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Parkinson’s Care Partners: Not Another “Self-Care” Discussion (Webinar Audio)
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54:28Being a care partner to someone with Parkinson’s disease (PD) can be a shifting and complex role, as symptoms and life circumstances change. And sometimes, this can lead to stress and even burnout for the care partner. Tune into audio from this Third Thursdays Webinar to hear expert panelists discuss how to navigate care partnership, including ever…
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The Role of Diet and Nutrition in Parkinson’s Disease and Brain Health with Puja Agarwal
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43:24It is widely known that a healthy diet can provide essential nutrients and lead to a multitude of benefits, but growing evidence has highlighted important links between diet, nutrition, and brain health, particularly related to neurodegenerative disease. In this episode, Dr. Puja Agarwal discusses her research investigating the role that diet and n…
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Developing a Novel App to Improve Speech Intelligibility in Parkinson's Disease with Gemma Moya-Galé
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44:46Parkinson's disease significantly impacts various aspects of communication, and this can make it challenging for people with the disease to communicate effectively, be understood by others, and engage in social situations. Dr. Gemma Moya-Galé joins this episode to talk about her work on voice and communication in people with Parkinson’s disease. In…
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MJFF Scientists Share How Their Work Could Transform Parkinson's Care
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19:57Understanding the biology of Parkinson’s disease (PD) and turning that knowledge into better treatments is a complex undertaking. In this episode of the award-winning Parkinson’s Science POV series, scientists at The Michael J. Fox Foundation (MJFF) discuss how they are tackling this problem from every angle. Whether it’s using cutting-edge imaging…
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Increasing Diversity in Research and Addressing Brain Health Inequities with Monica Rivera-Mindt
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45:04Certain populations are disproportionately affected by neurological diseases, including Parkinson's and other neurodegenerative diseases. A lot of work remains to be done to improve brain health outcomes and promote healthy brain aging across the lifespan, particularly for minoritized, underrepresented populations. Including participants from diver…
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Year of Momentum: What Parkinson’s Research Accomplished in 2024 (Webinar Audio)
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57:54With two new drugs approved by the FDA, a National Plan signed into law and many advances in our understanding of Parkinson’s disease, 2024 has been a transformative year in Parkinson’s research. Tune into audio from this month’s Third Thursdays Webinar to hear research experts from industry and academia talk with MJFF staff about the latest resear…
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The Development and Application of the Alpha-Synuclein Seed Amplification Assay with Claudio Soto
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38:26Alpha-synuclein plays a key role in the pathophysiology of Parkinson's disease, and researchers have been investigating this protein as a therapeutic target and also as a potential biomarker for the disease. The alpha-synuclein seed amplification assay, developed by Dr. Claudio Soto and colleagues, leverages the self-replicating nature of the misfo…
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Ask Us Anything About Deep Brain Stimulation Surgery Day
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40:34Each person living with Parkinson’s disease (PD) will have a unique journey with their treatments, including the decision to have deep brain stimulation (DBS), which is a surgical procedure to treat Parkinson’s motor symptoms. While DBS isn’t suitable for everyone, it can be helpful in the right person, and it’s a complex, lifelong choice. And alth…
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An Inside Look at the Edmond J. Safra Fellowship in Movement Disorders with Marcelo Merello and Sergio Castillo-Torres
58:53
58:53
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58:53To help meet the growing global need for more movement disorders specialists, The Michael J. Fox Foundation created the Edmond J. Safra Fellowship in Movement Disorders in collaboration with longtime partner the Edmond J. Safra Foundation. This program supports the training of movement disorders specialists who will provide expert care and drive ad…
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Hitting Stride: Research Advances on Walking with Parkinson’s (Webinar Audio)
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48:08Troubles with gait – slow walking, shuffling steps and foot dragging and more – can be symptoms of Parkinson’s. In audio from this Third Thursdays Webinar, our experts explore the robust research efforts underway to understand and treat gait issues, from physical rehab interventions to deep brain stimulation modifications to wearable robots designe…
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Creating Alpha-Synuclein Cell Lines and Supporting Open Science with Birgitt Schüle
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37:41Stem cell models derived from patients with Parkinson’s disease are valuable tools that are helping researchers around the world to better understand the underlying causes of neurodegeneration and to develop biomarkers and new therapies. To maximize the potential impacts of these tools, it is critical that they are developed and shared according to…
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Perspectives on Navigating Racial Bias and Stigma in Parkinson's Disease
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44:55In this podcast, four people from different backgrounds have a candid conversation on race, stigma and Parkinson’s. They share their experiences trying to find culturally competent medical professionals, overcoming the barriers to research participation, and communicating with their communities about their diagnosis. And they offer tips and advice …
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Developing FLEXISyn to Identify and Measure Changes in Alpha-Synuclein in Parkinson's Disease with Judith Steen
36:46
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36:46New qualitative and quantitative tools are being developed to measure and track changes in proteins relevant for neurodegenerative disease, and these tools have the potential to accelerate drug discovery and clinical trials. In this episode, Dr. Judith Steen discusses her work creating novel qualitative and quantitative tools and workflows at the i…
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A Conversation on Parkinson’s-Related Hallucinations and Delusions (Webinar Audio)
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54:03Parkinson’s disease brings with it many potential symptoms, including hallucinations (seeing things that are not there) and delusions (believing things that are not true). Not everyone will experience these symptoms and not everyone who does will find them bothersome, but it can be a source of uncertainty and concern for people living with the dise…
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Clinical Applications of Biomarkers and Large-Scale Collaborative Research with Charles Adler
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46:51Substantial research has focused on identifying biomarkers for the diagnosis of Parkinson's disease (PD) as well as monitoring progression of the disease. In developing these biomarkers, it is critical for scientists to consider how the biomarkers will ultimately be used in the clinic and in clinical trials research. In this interview, Dr. Charles …
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Investigating Light Therapy For Sleep and Motor Function in People with PD with Beatrix Feigl
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42:18Sleep disturbances, such as insomnia, sleep fragmentation, excessive daytime sleepiness, and REM sleep behavior disorder are common in people with Parkinson's disease (PD). Poor sleep quality can also impact other domains of function, including motor function. Prior research has shown that a type of photoreceptor cell in the retina, called melanops…
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Your Daily Dose: Managing Parkinson’s Medications (Webinar Audio)
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55:46Finding the right Parkinson’s treatment plan can be a trial-and-error process. The kind of medication, the dosage, the timing and lifestyle factors are all important pieces of the puzzle. In audio from this Third Thursdays Webinar, our expert panel made up of people living with Parkinson’s disease (PD), a movement disorder specialist and a research…
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The Autophagy-Lysosomal Pathway and Development of Relevant PD Biomarkers with Zhenyu Yue
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32:53Though existing evidence supports that dysfunction in the clearing of cellular debris plays an important role in the development of Parkinson's disease, many unanswered questions remain regarding the mechanisms of the autophagy-lysosomal pathway involved in this process. In particular, research in the field has been limited by a lack of reliable, q…
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Breathing Through: Mindfulness as a Parkinson's Treatment Tool
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45:21Research shows mindfulness and meditation can improve some Parkinson’s (PD) symptoms and help people live a better life with the disease, but it can be tricky to put into practice. In this podcast, you’ll hear from people whose lives have been touched by PD and who use mindfulness to reduce symptoms and stress, and from a researcher who is studying…
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Studying CSF Element Profiles and Tear Fluid as Potential Biomarkers, and Novel and Combined Therapies for PD with Paul Lingor
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48:27Evidence supports that dysfunction in the homeostasis of iron and other elements likely contributes to the pathophysiological mechanisms of Parkinson's disease, but we have yet to develop suitable elemental biomarkers for use in diagnosing and monitoring the progression of Parkinson's disease. Dr. Paul Lingor discusses his work in this area to iden…
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Considering Deep Brain Stimulation: What to Know and Expect (Webinar Audio)
56:47
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56:47The decision-making process around deep brain stimulation (DBS) to treat Parkinson’s motor symptoms can be a complex and emotional journey. People often have questions about when – and whether – to have the procedure and what the experience is like, from the months of evaluation pre-surgery to surgery day to life with the device. In audio from this…
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Current and Emerging Imaging Biomarkers for Diagnosis and Prognosis of PD and Atypical Parkinsonism with Antonio Strafella
38:27
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38:27Identifying reliable biomarkers for the diagnosis and prognosis of Parkinson's disease and atypical parkinsonism would have substantial impacts on clinical trials and clinical practice. A particularly active area of research is the development of novel molecular imaging biomarkers that can be used in combination with common neuroimaging approaches.…
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Building on the Biomarker Breakthrough: What We’re Working on Now
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34:58Just over a year ago, there was a major breakthrough in Parkinson’s disease (PD) research – a tool that could detect abnormal alpha-synuclein protein in the spinal fluid of people living with PD even before onset of symptoms. This discovery is already impacting the ways scientists conduct and think about Parkinson’s research. Tune into this episode…
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Examining Links Between Environmental Exposure, Poor Olfaction, and Parkinson's Disease with Honglei Chen
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47:45Prior studies have established links between poor olfaction and Parkinson's disease, and impaired sense of smell is a common prodromal symptom of Parkinson's disease. The causes and mechanisms of prodromal neurodegeneration are actively being researched. However, environmental exposure to pesticides or other chemicals may trigger or modify the cour…
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You Want to Volunteer for Parkinson’s Research: Now What? (Webinar Audio)
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58:31You might be interested in stepping forward for science to play a role in the next breakthrough in Parkinson’s research, but still have questions about how to actually participate. How do you pick the right study for you? How do you balance your life logistics and your medical care considerations? What rights do you have when you participate in a s…
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Developing Interventions to Improve Gait and Increase Physical Activity in Parkinson’s Disease with Gammon Earhart
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43:36Gait impairments such as slow speed, small steps, and high variability from step to step are common in people with Parkinson's disease, and these changes begin to occur early in the course of disease. Freezing of gait may develop later for some individuals, and it has been linked to falls and other adverse outcomes. When the quality of walking decl…
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Studying Basal Ganglia Circuits and Developing Deep Brain Stimulation Protocols for Longer-Lasting Effects with Aryn Gittis
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45:19Improving our understanding of the complex neural circuits involved in normal function of the basal ganglia and other parts of the brain impacted by Parkinson's disease is critical for developing more targeted and more effective treatment approaches. In this episode, Dr. Aryn Gittis discusses her research examining how the activity of specific basa…
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When Parkinson’s Hurts: Treatments for Managing Pain (Webinar Audio)
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57:53Many people living with Parkinson’s disease (PD) experience pain as a non-motor symptom. Pain can arise from stiff muscles, dystonia, nerve pain and even the disease progression itself. It’s a symptom that some find difficult to talk about, but there are options for people to find relief. In audio from this Third Thursdays webinar, listen to our ex…
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Innovative Fellowship Program is Training Tomorrow's Parkinson's Leaders with Rachel Dolhun
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41:09Demand for movement disorder specialists continues to grow, but not enough neurologists are receiving focused training in Parkinson’s and related conditions in order to meet the current and projected needs in the U.S. and around the world. In collaboration with longtime partner the Edmond J. Safra Foundation, The Michael J. Fox Foundation created t…
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What I Wish I Had Known at Diagnosis
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36:49In this episode, hosted by Larry and Rebecca Gifford, members of The Michael J. Fox Foundation’s Patient Council and their care partners share their honest reactions to their diagnosis — from panic and denial to sadness and loneliness. This group of men and women of different ages and backgrounds offers words of wisdom about what to consider, what …
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Real Talk from Women Living with Parkinson’s
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44:21In this raw and emotional conversation, four women with Parkinson’s living in four different countries discuss the challenges faced because of delayed diagnosis, hormonal changes, lack of information and treatment, research inequity and gender biases. They share how they live better with the disease by advocating for themselves with their health ca…
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Evidence Linking Parkinson's Disease Risk and Environmental Exposure to Trichloroethylene (TCE) with Sam Goldman
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40:21Trichloroethylene (TCE) and related chemicals like perchloroethylene (PCE) have been used widely for a variety of commercial purposes over the past century, and these chemicals are prevalent in the air, water, and soil. Over the past several decades, mounting evidence has been published linking exposure to TCE/PCE with adverse health effects, inclu…
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Let’s Talk Taboos: Hard-To-Discuss Parkinson’s Symptoms (Webinar Audio)
51:46
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51:46Living with Parkinson’s comes with a variety of symptoms, some of which can be unexpected, and frankly, embarrassing. Drooling, bladder issues and sexual dysfunction are hard to talk about, even with loved ones or your doctor – and can affect your self-image, your intimate relationships or the way you move through the world. In audio from this Thir…
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New Advances in Neurosurgical Interventions for Parkinson's Disease with Doris Wang
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41:26For over a century, different surgical interventions have been explored to address symptoms of Parkinson's disease, and researchers are continuing to innovate and improve surgical treatments today. With new technology and an ever-expanding understanding of the function of the nervous system and the pathophysiology of Parkinson's disease, neurosurgi…
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Accelerating Discovery by Developing and Distributing Research Tools with Nicole Polinski
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34:41The Michael J. Fox Foundation for Parkinson's Research established its Research Tools Program to address gaps in the field and common challenges surrounding the development of reagents and models that slowed the initial stages of promising research projects. In collaboration with many partners and stakeholders, the Research Tools Program helps ensu…
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Everyday Exposures to Parkinson’s: Environmental Connections to the Disease (Webinar Audio)
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59:07The biology behind what causes Parkinson’s is complex, with only about a quarter of cases with clear genetic drivers. The environment – where you live, the air you breathe, the food you eat, the world around you – plays a key role in PD. Emerging research is showing environmental exposures to things like pesticides and pollution may interact with a…
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The Importance of Sex and Gender Factors in Neurodegenerative Disease Research and Care with Antonella Santuccione Chadha
47:31
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47:31Increasing evidence supports the presence of sex and gender differences in neurodegenerative conditions, including Alzheimer's disease and Parkinson's disease. There is a critical need to more closely examine sex and gender differences in all stages of research, therapeutic development, and clinical treatment to enable better outcomes through preci…
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Understanding Genetics, Pathology, and Progression in Parkinson's Disease and Atypical Parkinsonian Syndromes with Huw Morris
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44:53Atypical Parkinsonian Syndromes, such as progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration (CBD), and dementia with Lewy bodies are often initially diagnosed as Parkinson's disease. Incorrect, incomplete, or delayed diagnoses are barriers to beginning the most appropriate treatment early in the disease c…
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