Beste The Long Run With Luke Timmerman Podcasts (2025)

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Ep187: Eric Fischer on Creating a New Class of Medicines 1:05:48

4d ago1:05:48

1:05:48

Eric Fischer, a professor at Dana-Farber Cancer Institute, on creating a new class medicines -- targeted protein degraders.Von Timmerman Report

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Ep186: Bruce Levine & Mags McCarthy on a Song About Science and Hope 1:02:33

19d ago1:02:33

1:02:33

Bruce Levine, a CAR-T cell therapy researcher at the University of Pennsylvania, and Mags McCarthy, a country music star, discuss their new song about science and hope for cancer patients.Von Timmerman Report

1
Ep185: Dr. Lachelle Weeks on Predicting Leukemia Risk At Scale 1:05:47

1M ago1:05:47

1:05:47

Dr. Lachelle Weeks is a physician-scientist at Dana-Farber Cancer Institute working on a project to predict leukemia risk based on widely available blood samples.Von Timmerman Report

1
Ep184: Jen Adair on Affordable, Accessible Gene & Cell Therapies 1:50:23

2M ago1:50:23

1:50:23

Jen Adair, professor and associate director of the Horae Gene Therapy Center at the University of Massachusetts Chan Medical School, on creating more affordable and accessible cell and gene therapies.Von Timmerman Report

1
Ep183: Sabah Oney on CAR-T Cells Against Solid Tumors 56:23

2M ago56:23

56:23

Sabah Oney, CEO of Philadelphia and San Francisco-based Dispatch Biotherapeutics, on engineering CAR-T cells that can kill solid tumors.Von Timmerman Report

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Ep182: Andy Rachleff & Yung Lie on Creative Ways to Back Science 1:01:18

3M ago1:01:18

1:01:18

Andy Rachleff and Yung Lie, board chair and CEO of Damon Runyon Cancer Research Foundation, on creative ways to support science amid budget cuts.Von Timmerman Report

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Ep181: Claire Mazumdar on a Two-Pronged Attack Against Cancer 57:18

4M ago57:18

57:18

Claire Mazumdar, CEO of Boston-based Bicara Therapeutics, on developing a bifunctional antibody for head and neck cancer.Von Timmerman Report

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Ep180: John Rinn on Discovering Drugs Based on Long Non-Coding RNA 1:10:45

4M ago1:10:45

1:10:45

John Rinn, professor at the University of Colorado and co-founder of Lincswitch Therapeutics, on exploring long non-coding RNA.Von Timmerman Report

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Ep179: Ethan Weiss & Josh Lehrer on a New Idea for Cardiovascular Disease & Diabetes 1:03:25

5M ago1:03:25

1:03:25

Marea Therapeutics CEO Josh Lehrer and CSO Ethan Weiss on a new angle of attack against cardiovascular disease and diabetes.Von Timmerman Report

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Ep178: Peyton Greenside on ML-Guided Biologics Discovery 1:02:56

5M ago1:02:56

1:02:56

Peyton Greenside, co-founder and CEO of BigHat Biosciences, on machine-learning guided biologic drug discovery.Von Timmerman Report

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Ep177: Kevin Parker on Finding Cancer Drug Targets 58:13

6M ago58:13

58:13

Kevin Parker, CEO of Cartography Biosciences, on finding new cancer drug targets.Von Timmerman Report

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Ep176: David Roblin on Building a TechBio Company 1:19:28

7M ago1:19:28

1:19:28

David Roblin, CEO of London-based Relation Therapeutics, on building a techbio discovery company.Von Timmerman Report

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Ep175: Andy Scharenberg on in vivo CAR-T cell therapies 1:10:46

7M ago1:10:46

1:10:46

Andy Scharenberg, CEO of Seattle-based Umoja Biopharma, on developing in vivo CAR-T cell therapies.Von Timmerman Report

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Ep174: Najat Khan on the TechBio Movement 1:07:16

8M ago1:07:16

1:07:16

Najat Khan, chief R&D and chief commercial officer of Recursion, on using technology to improve drug discovery.Von Timmerman Report

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Ep173: Robert Blum on Building a Fully Integrated Biopharma For Muscle Disorders 57:56

8M ago57:56

57:56

Robert Blum, CEO of South San Francisco-based Cytokinetics, on building a fully integrated biopharma to treat muscle disorders.Von Timmerman Report

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Ep172: Mostafa Ronaghi on Studying Live Cells at Scale 1:20:53

9M ago1:20:53

1:20:53

Mostafa Ronaghi, co-founder and executive board member of Cellanome, on developing technology to look at live cells and cellular interactions at scale.Von Timmerman Report

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Ep171: Ram Aiyar on RNA Editing Medicines 1:01:48

9M ago1:01:48

1:01:48

Ram Aiyar, CEO of Cambridge, Mass.-based Korro Bio, on RNA editing medicines.Von Timmerman Report

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Ep170: David Schenkein on Investing in the Future of Biotech 59:52

10M ago59:52

59:52

David Schenkein, general partner at GV, on investing in the future of biotech.Von Timmerman Report

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Ep169: Kevin Fitzgerald on the Past & Future of RNAi Medicines 1:02:28

10M ago1:02:28

1:02:28

Alnylam Pharmaceuticals chief scientific officer Kevin Fitzgerald on the past, present & future of RNA interference medicines.Von Timmerman Report

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Ep168: Jonathan Bricker on How to Quit Smoking & Prevent Cancer 1:00:23

11M ago1:00:23

1:00:23

Jonathan Bricker, professor in the cancer prevention program at Fred Hutchinson Cancer Center, on how to quit smoking with help from tech and biotech tools.Von Timmerman Report

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Ep167: Leslie Williams on transfer RNA therapies 1:11:28

12M ago1:11:28

1:11:28

Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.Von Timmerman Report

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Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity 1:03:35

1y ago1:03:35

1:03:35

Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.Von Timmerman Report

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Ep165: Zach Hornby on Tackling Cancer Drug Resistance 1:02:45

1y ago1:02:45

1:02:45

Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.Von Timmerman Report

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Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients 56:39

1y ago56:39

56:39

Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.Von Timmerman Report

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Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases 1:08:19

1y ago1:08:19

1:08:19

Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.Von Timmerman Report

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Ep162: Sean McClain on AI for Biologic Drug Discovery 1:05:59

1+ y ago1:05:59

1:05:59

Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.Von Timmerman Report

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Ep161: Jeff Stein on a Long-Lasting Flu Drug 1:08:51

1+ y ago1:08:51

1:08:51

Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.Von Timmerman Report

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Ep160: Abe Ceesay on Precision Neuroscience 1:08:48

1+ y ago1:08:48

1:08:48

Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.Von Timmerman Report

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Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease 1:07:22

1+ y ago1:07:22

1:07:22

Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.Von Timmerman Report

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Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery 1:00:44

1+ y ago1:00:44

1:00:44

David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.Von Timmerman Report

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Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery 56:33

1+ y ago56:33

56:33

Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.Von Timmerman Report

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Ep156: David Liu on New Tools and Techniques for Biology 1:52:57

1+ y ago1:52:57

1:52:57

David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.Von Timmerman Report

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Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's 1:02:37

1+ y ago1:02:37

1:02:37

Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.Von Timmerman Report

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Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer 1:03:14

1+ y ago1:03:14

1:03:14

Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.Von Timmerman Report

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Ep153: Rick Young on Studying Gene Expression for Drug Discovery 1:01:43

1+ y ago1:01:43

1:01:43

Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.Von Timmerman Report

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Ep152: Jens Eckstein on Investing in Healthy Aging 1:05:05

2y ago1:05:05

1:05:05

Jens Eckstein, investment partner at Hevolution Foundation, on investing in healthy aging.Von Timmerman Report

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Ep151: Shelley Force Aldred and Nathan Trinklein on Bispecific Antibodies for Cancer 1:03:55

2y ago1:03:55

1:03:55

Shelley Force Aldred and Nathan Trinklein, co-founders of Rondo Therapeutics, on the opportunity with bispecific antibodies for cancer.Von Timmerman Report

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Ep150: Jeff Jonker on the Small Molecule Drug Discovery Renaissance 1:03:48

2y ago1:03:48

1:03:48

Jeff Jonker, CEO of San Diego-based Belharra Therapeutics, on the renaissance in small molecule drug discovery.Von Timmerman Report

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Ep149: Nancy Stagliano on Precision Neuroscience 1:01:53

2y ago1:01:53

1:01:53

Nancy Stagliano, CEO of South San Francisco-based Neuron23, on bringing precision medicine to neuroscience drug discovery.Von Timmerman Report

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Ep148: Diana Brainard on the Fight Against Infectious Disease 1:03:27

2y ago1:03:27

1:03:27

Diana Brainard, CEO of AlloVir, on leading the fight against infectious diseases.Von Timmerman Report

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Ep147: Reid Huber on Investing in the Future of Medicine 1:08:41

2y ago1:08:41

1:08:41

Reid Huber, partner at Third Rock Ventures, on investing in the future of medicine.Von Timmerman Report

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Ep146: Jeff Huber on Life in Tech and Biotech 1:47:05

2y ago1:47:05

1:47:05

Jeff Huber, co-founder and general partner at Triatomic Capital, on his career path in tech, and then biotech.Von Timmerman Report

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Ep145: Lori Lyons-Williams on Targeted Radiopharmaceuticals for Cancer 1:06:39

2y ago1:06:39

1:06:39

Lori Lyons-Williams, CEO of Abdera Therapeutics, on developing targeted radiopharmaceuticals for cancer.Von Timmerman Report

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Ep144: Turning the Tables, Rob Perez Interviews Me 1:04:58

2y ago1:04:58

1:04:58

Turning the Tables, Rob Perez Interviews MeVon Timmerman Report

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Ep143: Zach Weinberg and Alexis Borisy on Freeing the Biotech Founders 1:10:25

2y ago1:10:25

1:10:25

Zach Weinberg and Alexis Borisy of Curie.Bio on Freeing the Biotech FoundersVon Timmerman Report

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Ep142: Fred Appelbaum on how 'Living Medicine' Came to Be 55:54

2y ago55:54

55:54

Fred Appelbaum, a physician, scientist and leader at the Fred Hutchinson Cancer Center, on 'Living Medicine,' his new book about the development of bone marrow transplantation and the rise of cell therapy.Von Timmerman Report

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Ep141: Colin Hill on Digging Deep into Data, Finding New Drug Targets 1:09:30

2y ago1:09:30

1:09:30

Colin Hill, co-founder and CEO of Aitia, on digging deep into biological datasets and finding new drug targets.Von Timmerman Report

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Ep140: Yung Lie on Supporting Young Scientists with Bold, Brave Ideas 1:02:40

2y ago1:02:40

1:02:40

Yung Lie, president and CEO of Damon Runyon Cancer Research Foundation, on advancing cancer research by supporting young scientists with bold and brave ideas.Von Timmerman Report