The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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"web3 with a16z" is a show about the next generation of the internet, and about how builders and users -- whether artists, coders, creators, developers, companies, organizations, or communities -- now have the ability to not just "read" (web1) + "write" (web2) but "own" (web3) pieces of the internet, unlocking a new wave of creativity and entrepreneurship. Brought to you by a16z crypto, this show is the definitive resource for understanding and going deeper on all things crypto and web3. Fro ...
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a16z Live is the place to listen to recorded live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too). As a reminder, all content posted here is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Views expressed are those of the individuals and not the views of Andreessen Horowitz, please see a16z.com/disclosures for more. To learn more about the broader a16z Podcast network and ...
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16 Minutes on the News is a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This ...
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Super Staffing Healthcare, Codifying Compliance, & Scaling Services
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52:09
As we prepare to step into 2025, the possibilities for applied AI are reshaping industries in profound ways. In this episode, a16z General Partners Julie Yoo and Angela Strange, and Partner Joe Schmidt, dive into the transformative power of AI across healthcare, fintech, and traditional service sectors. We explore: Super Staffing for Healthcare: Ho…
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Trends for 2025 (part 2): AI x Crypto - From Agents in Games & DePIN to Proof of Personhood and More
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40:05
with @carrawu @eddylazzarin @0xkarmacoma and @smc90 @rhhackett Welcome to our special end-of-year episodes -- which also look ahead to 2025 -- covering our annual Big Ideas lists, where various a16z crypto team members share what they are personally excited about. (You can see the firmwide list, also including all the trends of the crypto team, her…
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How Jack Henry is Modernizing Banking Infrastructure
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26:38
Most financial institutions still bank on software built before the internet, but Jack Henry's CTO, Ben Metz, is leading a quiet revolution to change that. Speaking with a16z General Partner Angela Strange, Metz shares how banks’ historical tech infrastructure and regulatory obstacles have stymied innovation—and how Jack Henry is helping them overc…
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The Race for AI—Search, National Infrastructure, & On-Device AI
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42:45
The AI race is on, and 2025 could be its most transformative year yet. In this episode, a16z General Partners Anjney Midha and Jennifer Li, and Partner Alex Immerman dive into the trends reshaping AI and its impact on search, infrastructure, and devices. We explore: How AI-native tools like ChatGPT and Perplexity are challenging Google’s search dom…
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Trends for 2025 (part 1): Stablecoins, App Stores, UX, and More
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33:52
with @sambroner @meigga @darenmatsuoka @jneu_net @chrislyons and @rhhackett @smc90 Welcome to our special end-of-year episodes -- which also look ahead to 2025 -- covering our annual Big Ideas lists, where various a16z crypto team members share what they are personally excited about. (You can see the firmwide list, also including all the trends of …
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Jobs of the Future, Harnessing Earth Observation, & Gaming Tech Advances
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41:59
As 2025 begins, industries are evolving at unprecedented speed: robots are revolutionizing manufacturing, terabytes of earth observation data are driving new possibilities, and gaming technology is transforming how we design, train, and innovate across sectors. In this episode, a16z General Partner Erin Price-Wright, Engineering Fellow Millen Anand…
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Scaling Shopify: Tobias Lütke and Ben Horowitz on Building a Global Giant
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45:26
In this episode of Web3 with a16z, Shopify CEO and cofounder Tobias Lütke joins a16z cofounder Ben Horowitz for a conversation recorded live at the a16z crypto Founders Summit. Together, they explore what it takes to build a breakout startup in a competitive market, the changing landscape of retail, and how to drive workplace change while navigatin…
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Building a $20B+ Open Source Business with MongoDB's Eliot Horowitz
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40:16
a16z Partner Seema Amble talks with MongoDB and Viam co-founder Eliot Horowitz about building sustainable open source software tools. From challenging Oracle to building the de facto cloud-based database management tool, Horowitz outlines MongoDB’s early go-to-market strategies, approach to community building, and enterprise sales motion. This epis…
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How AI is Transforming Labor Markets
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Did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero? In this episode General Partners Alex Rampell, David Haber, and Angela Strange discuss how AI is revolutionizing labor by automating tasks traditionally done by humans. They’ll trace the evolution of cloud eras — from…
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How Zapier Became Profitable in 3 years and Scaled to $5B with Wade Foster
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31:59
a16z Partner Seema Amble connects with Zapier co-founder Wade Foster about the company’s founding and GTM success utilizing a product-led growth (PLG) strategy. Chock-full of actionable insights, this episode explores Zapier’s product strategy, customer experience, and how the team built a sustainable growth engine that enabled them to reach profit…
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Fixing Education in America: What's Stopping Us?
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40:39
Over half of Americans live in childcare deserts, while 90% of brain development happens before the age of five. All the while, education and childcare remain among the most resistant sectors to technological change. Billions of dollars have been spent, but outcomes continue to lag. Why? In this episode, we dive into the systemic issues—misaligned …
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How Gusto Used Customer Input to Scale Growth with Tomer London
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30:34
In this episode, a16z Partner Seema Amble chats with Tomer London, co-founder of Gusto, about establishing product-market fit and product discovery. London shares how Gusto, now valued at ~$10 billion with 300,000+ customers, identified early customers who could provide valuable feedback that helped the team optimize the self-service product experi…
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Prediction Markets and Beyond
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1:49:49
This episode was originally published on our sister podcast, web3 with a16z. If you’re excited about the next generation of the internet, check out the show: https://link.chtbl.com/hrr_h-XC We've heard a lot about the premise and the promise of prediction markets for a long time, but they finally hit the main stage with the most recent election. So…
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Death of a Salesforce: Why AI Will Transform Sales
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16:34
Sales is evolving. AI-native systems are replacing traditional CRM tools, capturing unstructured insights from emails, Slack, surveys, and more in real time. These systems automate early-stage tasks like prospecting and qualification, enabling sales teams to focus on high-value work—while AI provides live coaching and drives decisions across sales,…
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Prediction Markets and Beyond
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1:48:05
with @atabarrok @skominers @smc90 We've heard a lot about the premise and the promise of prediction markets for a long time, but they finally hit the main stage with the most recent election. So what worked (and didn't) this time? Are they better than pollsters, journalists, domain experts, superforecasters? So in this conversation, we tease apart …
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The Longevity Imperative: Redefining the Way We Age
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40:30
What if the biggest challenge of our time isn’t living longer, but living better? In this episode, we’re tackling one of humanity’s greatest accomplishments—and perhaps its most overlooked challenge: longevity. As more people live past 100, our systems—healthcare, finance, career planning, and even our cultural perceptions of aging—need a fundament…
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Rebuilding America's Industrial Backbone
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32:34
America is a country of immense wealth, but our manufacturing infrastructure is struggling to keep pace. In this episode, we discuss the overlooked crisis of American manufacturing and what it means for our national resilience. a16z’s Oliver Hsu hosts a conversation with founders Jordan Black (Senra Systems), Chris Power (Hadrian), and Bryon Hargis…
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Autonomy Across Air, Land, and Sea
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48:18
2024 has been a milestone year for autonomous tech. Waymo’s fully autonomous driver has surpassed 20 million miles, while FAA approvals now allow commercial drones to fly without visual observers, advancing air autonomy in unprecedented ways. In this special live recording from SF Tech Week, a16z partner Erin Price-Wright moderates a panel of exper…
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Government... By Lottery?
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with @baileyflan @ahall_research @rhhackett Today we’re dusting off an ancient practice that has become trendy once again: the old-but-new idea of “sortition,” or selecting representatives by lottery. Sortition was used in ancient Athenian democracy to elect public officials. It’s also been lately revived by tech companies like Meta and AI startups…
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How to Build a Thriving AI Ecosystem with Lisa Su, CEO of AMD
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High-performance compute is the bedrock of generative AI, and if there’s anyone who knows about high-performance chips, it’s AMD CEO Lisa Su. In this wide-ranging conversation with a16z Operating Partner Bob Swan—himself formerly CEO of Intel—Lisa lays out her vision for the evolution of compute within the AI ecosystem, touching not only on raw pow…
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State of Crypto 2024: Builder Energy, U.S. Election, Stablecoins, AI, More
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54:19
We take you behind the scenes of our newly released, annual State of Crypto Report — a16z crypto's analysis of the latest data and trends that have defined the industry in 2024. This year's report features some brand new insights, from estimating the number of real crypto users globally, to understanding how much interest in crypto swing states may…
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with @pmarca @bhorowitz Today we’re running a special episode featuring a16z cofounders Marc Andreessen and Ben Horowitz talking about AI bots and crypto. They discuss what happens when you mix postmodern theories and internet memes in an LLM. They also get into the sudden rise of a strange memecoin, the state of crypto regulation in the U.S., and …
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Tesla's Road Ahead: The Bitter Lesson in Robotics
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What does Rich Sutton’s "Bitter Lesson" reveal about the decisions Tesla is making in its pursuit of autonomy? In this episode, we dive into Tesla’s recent "We, Robot" event, where they unveiled bold plans for the unsupervised full-self-driving Cybercab, Robovan, and Optimus—their humanoid robot, which Elon Musk predicts could become “the biggest p…
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The Story of Apple Pay with Jennifer Bailey
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31:53
In 2024, marking 10 years since its launch, Apple Pay now boasts hundreds of millions of consumers in 78 markets, at checkout on millions of websites and apps, in tens of millions of stores worldwide, and is supported by more than 11,000 bank and network partners. In this episode, a16z General Partner Alex Rampell sits down with Jennifer Bailey, VP…
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State of Crypto 2024: Builder Energy, U.S. Election, Stablecoins, AI, More
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53:24
with @DarenMatsuoka @eddylazzarin @rhhackett Welcome to web3 with a16z. Today we're taking you behind the scenes of our newly released, annual State of Crypto Report — a16z crypto's analysis of the latest data and trends that have defined the industry in 2024. This year's report features some brand new insights, from estimating the number of real c…
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Building a Thriving AI Ecosystem with Lisa Su
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Lisa Su has transformed AMD into a global leader in AI and high-performance computing. In this episode of the AI Revolution (AIR) series , Bob Swan, a16z Operating Partner and former CEO of Intel, sits down with Lisa Su, CEO of AMD, to discuss how her leadership has propelled AMD’s growth and positioned the company at the forefront of AI innovation…
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a16z Growth's David George on His Frameworks for Late-Stage Investing
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58:31
Finding and backing companies that can reach escape velocity is the name of the game over here at a16z Growth—but picking those winners is far from easy. David George, head of the a16z Growth fund, sat down with the I/O podcast to discuss his mental models for growth-stage investing, what it really takes to go public, where AI is today and where it…
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The Deepfake Dilemma: The Technology, Policy, and Economy
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Deepfakes—AI-generated fake videos and voices—have become a widespread concern across politics, social media, and more. As they become easier to create, the threat grows. But so do the tools to detect them. In this episode, Vijay Balasubramaniyan, cofounder and CEO of Pindrop, joins a16z’s Martin Casado to discuss how deepfakes work, how easily the…
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A Big Week in Tech: NotebookLM, OpenAI’s Speech API, & Custom Audio
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Last week was another big week in technology. Google’s NotebookLM introduced its Audio Overview feature, enabling users to create customizable podcasts in over 35 languages. OpenAI followed with their real-time speech-to-speech API, making voice integration easier for developers, while Pika’s 1.5 model made waves in the AI world. In this episode, w…
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Why Human Data is Key to AI: Alexandr Wang from Scale AI
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In this conversation with a16z general partner David George, Scale AI founder and CEO Alexandr Wang discusses the three pillars of AI—models, compute, and data—and how creating abundant data is core to the evolution of gen AI. With Scale’s work across enterprise, automotive, and the public sector, Alex is also building the critical infrastructure t…
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From Swipe to Scale: How Tinder Became #1
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28:32
In 1995, just 2% of couples met online. Today, that number has surged to over 50%, making online dating the top way couples connect. In this episode, a16z General Partner Andrew Chen chats with Tinder founder Sean Rad about how he built an app that changed culture. Sean shares why seamless experiences matter, how startups often get marketing wrong,…
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Bridges: Out of the Mess, Into the Meshnet (with LayerZero)
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41:43
Welcome to web3 with a16z. Today we explore the messy secrets of blockchain bridges. These cross-chain connectors are the go-betweens in today's multichain world, but their short history has been a checkered one, with prominent projects succumbing to major hacks and other hijinks. So we've brought on one of the builders who knows this world best to…
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In the Vault: Assessing AI Impact vs. Hype with John Stecher of Blackstone
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23:25
a16z general partner David Haber talks to John Stecher, Chief Technology Officer at Blackstone, where he advances cutting-edge technology, heads up innovation investing, and advises the firm’s investment teams and portfolio companies. The conversation covers how he decides whether to build tech in-house or partner with startups, what qualities he’s…
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Human Data is Key to AI: Alex Wang from Scale AI
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30:56
What if the key to unlocking AI's full potential lies not just in algorithms or compute, but in data? In this episode, a16z General Partner David George sits down with Alex Wang, founder and CEO of Scale AI, to discuss the crucial role of "frontier data" in advancing artificial intelligence. From fueling breakthroughs with complex datasets to navig…
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The Frontier of Spatial Intelligence with Fei-Fei Li
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44:40
Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, our guests have long been laying the groundwork for innovations that are transforming industries today. In this episode, a16z General Partner Martin Casado joins Fei-Fei and Justin to explore the journey from early AI winters to the…
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Apple’s Big Reveals, OpenAI’s Multi-Step Models, and Firefly Does Video
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31:55
This week in consumer tech: Apple’s big reveals, OpenAI’s multi-step reasoning, and Adobe Firefly’s video model. Olivia Moore and Justine Moore, Partners on the a16z Consumer team, break down the latest announcements and how these product launches will shape the tech ecosystem, transform AI-powered experiences, and impact startups competing for att…
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Games as Reality (with EVE Online)
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35:59
with @HilmarVeigar @eddylazzarin Our featured guest today is Hilmar Pétursson, the CEO of CCP Games, maker of EVE Online, a massive multiplayer online role playing game. In this episode, Pétursson shares his unique world view and game-making philosophy, as well as a deep dive into the technology and economic design of his sci-fi simulation. He also…
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How Blockchain Tech Advances Benefit Other Industries
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with Dan Boneh @tim_roughgarden @smc90 In this special 50th episode of the web3 with a16z podcast, we discuss how work in the blockchains/ crypto space has led to advances in several important technologies — which can be (and are being) used by many other industries beyond crypto. Tim Roughgarden (a16z crypto Head of Research and professor at Colum…
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Grand Challenges in Healthcare AI
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37:40
Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to discuss the grand challenges facing healthcare AI today. The talk through the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the opportunity for innovation in clinical trials. The…
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Governing democracy, the internet, and boardrooms
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with @NoahRFeldman, @ahall_research, @rhhackett Welcome to web3 with a16z. I'm Robert Hackett and today we have a special episode about governance in many forms — from nation states to corporate boards to internet services and beyond. Our special guests are Noah Feldman, constitutional law scholar at Harvard who also architected the Meta oversight …
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It’s Time to Build in Healthcare
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41:04
Half of prescribed medications are never taken, and 88% of Americans are metabolically unhealthy. Despite spending 20% of our GDP on healthcare—twice that of any other developed nation—our outcomes still lag behind. In this episode, we explore why technologists must step into the healthcare ring. Solving medicine isn’t enough; we need to make healt…
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Latin America: A Tech Powerhouse?
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33:07
Latin America is emerging as a tech powerhouse, but it's not a one-size-fits-all market. In this episode, we explore why what works in Argentina won’t necessarily fly in Brazil or Mexico, and how companies are adapting to these unique regional dynamics. Join Dileep Thazhmon, Cofounder and CEO of Jeeves; Santiago Suarez, Cofounder and CEO of Addi; G…
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In the Vault: AI and Banking Innovation with Tim Karpoff of Citi
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24:12
a16z general partner David Haber and fintech partner Marc Andrusko talk to Tim Karpoff, the Global Head of Strategy at Citi, where he guides the bank’s core focus areas, as well as future investment in emerging tech like AI. The conversation covers the shifting landscape of banking policy and regulation, the increasingly important role startups are…
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The SSN Breach: What Now?
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22:22
In this episode, we cover the recent data breach of nearly 3B records, including a significant number of social security numbers. Joining us to discuss are security experts Joel de la Garza and Naftali Harris. Incredibly enough, Naftali and his team were able to get their hands on the breached dataset and were able to validate the nature of the cla…
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Governance Attack!?
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with @ahall_research @eddylazzarin @0xShuel @smc90 In this episode, we cover both recent events + evergreen governance questions in political systems: Specifically, we breakdown the recent Compound “governance attack”... as well as the broader topic of DAO governance and voting in general. We also discuss how to avoid, prevent, and respond to such …
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Building Innovation Hubs: The UK & Beyond
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45:44
This episode from Web3 with a16z Crypto, is all about innovation on a global scale, exploring both ecosystem and individual talent levels. We examine what works and what doesn’t, how certain regions evolve into startup hubs and economic powerhouses, and what constitutes entrepreneurial talent. We also discuss the nature of ambition, the journey to …
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Building the World’s Most Trusted Driver with Waymo's Dmitri Dolgov
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36:42
Waymo co-CEO Dmitri Dolgov joined a16z general partner David George to discuss how Waymo is using genAI to help them build safer, sustainable, and more accessible transportation. In the conversation, Dmitri talks about the potential of embodied AI, the value of simulations and building training data, and his approach to leading a company focused on…
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The Olympics of Talent: France's Tech Boom
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37:02
Once criticized for lacking ambition, French founders are now aiming to create the world’s largest companies. With a thriving ecosystem attracting talent from across Europe and the US, France is becoming a major player on the global stage. In this episode, we cover the unique advantages of building startups in France. Roxanne Varza, Director of Sta…
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with @eddylazzarin @milesjennings @rhhackett Today’s episode covers all things tokens — that includes what tokens have to do with decentralized protocols, understanding the different types of tokens, and, of course, the Do's and Don'ts of designing and launching a token. Our guests are a16z crypto chief technology officer Eddy Lazzarin, as well as …
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Bringing Production-Ready GenAI to the Enterprise
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32:02
As genAI expands through the enterprise, many leaders are figuring out how to evolve their genAI prototypes into production-ready tools. Pinecone CEO Edo Liberty and LangChain CEO Harrison Chase discuss which parts of the stack to build or buy, how to improve out-of-the-box models by helping customers select and ingest the right data, and picking t…
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