Stem Cells: Dr. Jekyll or Mr Hyde?

Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

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HARNACK LECTURE Stem Cells: Dr. Jekyll or Mr Hyde? Speaker: Hans Clevers, M.D., Ph.D. (https://www.hubrecht.eu/onderzoekers/clevers-group/), Professor of Molecular Genetics, Hubrecht Institute Director Research, Princess Maxima Center for Pediatric Oncology (Utrecht). Stem cells are the foundation of all mammalian life, building and maintaining our bodies throughout life. Hans Clevers and his group have identified a gene (lgr5) that marks a series of known and novel adult stem cells, in organs such as the gut, the liver, the lung, and the pancreas. They have learned to grow these stem cells in a dish into mini-versions of the human organs from which they derive. This so called organoid technology opens a range of avenues for the study of development, physiology and disease as well as for personalized medicine. In the long run, cultured mini-organs may replace transplant organs from donors and hold promise in gene therapy. Video of the Harnack Lecture 2017 Stem Cells: Dr. Jekyll or Mr Hyde? (https://youtu.be/TJ4TRD2BWXg) The Harnack Lecture is an honorary event organized by the Max Planck Society to commemorate Adolf von Harnack (1851 to 1930), the German science reformer. Hans Clevers, M.D., Ph.D. © MPG / Fotograf: Ausserhofer Produced by Voice Republic For more podcasts visit http://voicerepublic.com

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