On this episode, we review COPD and its clinical presentations, etiologies, pathophysiology, and management. We discuss the newly updated 2025 GOLD guidelines for the treatment of COPD. We compare and contrast the efficacy, safety profiles, and appropriate use of bronchodilators, inhaled corticosteroids, and other COPD therapies in different stages…

On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing pulmonary arterial hypertension. We compare and contrast the efficacy, safety profiles, and appropriate use of targeted PAH therapies, adjunct treatments, and patient monitoring techniques. Cole and I are happy to share that our listeners can claim …

On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing rheumatoid arthritis. We compare and contrast the efficacy, safety profiles, and appropriate use of disease-modifying antirheumatic drugs (DMARDs), biologics, and other therapies as well as discuss patient-specific treatment strategies considering f…

On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing heart failure (primarily focusing on HFrEF). We compare and contrast the efficacy, safety profiles, and appropriate use of heart failure medications. We also review some of the landmark clinical trials that were used when developing the heart failur…

On this episodes, we review some of the key updates in the 2025 American Diabetes Association treatment guidelines and their implications for clinical practice. We discuss the treatment algorithm for type-2 diabetes as well as compare the efficacy, safety profiles, and patient-specific considerations of current diabetes treatment options. 2025 ADA …

On this episode, we discuss define food allergies and describe their clinical presentations, underlying pathophysiology, and diagnostic criteria. We also compare and contrast treatment and prevention approaches, including dietary adjustments and allergen-specific immunotherapy. We also biefly review Celiac disease. Cole and I are happy to share tha…

On this episode, we evaluate the current guidelines and evidence-based treatment strategies for managing atopic dermatitis. We compare and contrast the efficacy, safety profiles, and appropriate use of various therapies. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast epi…

On this episode, we discuss allergic rhinitis and describe its clinical presentations, common triggers, and pathophysiology. We compare and contrast the efficacy, safety profiles, and appropriate use of antihistamines, intranasal corticosteroids, immunotherapy, and environmental control measures in treating allergic rhinitis. Free - Pyrls Nasal Cor…

On this episode, we discuss the prevention and management of opportunistic infections in patients with HIV and other immunocompromising conditions. We provide an overview of the various strategies for managing common OIs, including pharmacological treatments and preventive measures. We also compare and contrast the efficacy, safety profiles, and ap…

On this episode we discuss the diagnosis and management of axial spondyloarthritis. We begin by defining axial spondyloarthritis (radiographic axial sponyloarthropathy AKA ankylosing spondylitis vs non-radiographic axial sponyloarthropathy) and describe its clinical presentations, etiologies, and pathophysiology. We then compare and contrast the ef…

On this episode, we discuss dermatophyte infections. We review their clinical presentations, etiologies, and pathophysiology. We compare and contrast the efficacy, safety profiles, and appropriate use of antifungal therapies, lifestyle modifications, and patient monitoring involved with treatment. Cole and I are happy to share that our listeners ca…

On this episode, we discuss Crohn's disease. We describe the clinical presentations, etiologies, and the pathophysiology. We compare and contrast the efficacy, safety profiles, and appropriate use of biologic therapies, immunomodulators, and corticosteroids in treating Crohn's disease. We also review the development of patient-specific treatment st…

On this episode, we discuss the management of migraines. We begin with background info including clinical presentations, potential triggers, and pathophysiology. We review the current guidelines and evidence-based treatment strategies, including pharmacological and non-pharmacological interventions. We then compare and contrast the efficacy, safety…

On this episode, we describe the clinical presentation, etiology, and pathophysiology of asthma. We review current guidelines and evidence-based treatment strategies for managing asthma, including pharmacological and lifestyle interventions. Our hope is that this material will help the listener to develop patient-specific treatment strategies consi…

On this episode we discuss the management of opioid use disorder. We begin by describing its clinical presentations, etiologies, and pathophysiology. We then compare and contrast the efficacy, safety profiles, and appropriate use of medications for opioid use disorder, behavioral therapies, and patient monitoring in treating opioid use disorder. Co…

On this episode, we review the treatment options and management strategies for primary hypertension. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continui…

On this episode, we discuss the management of endometriosis. We review some background information as well as the various treatment options and the treatment algorithm. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com t…

On this episode we discuss both purlent and non-purlent skin and soft tissue infections. We also use this episode to review various antimicrobial agents. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide liste…

On this episode, we discuss the management of a few different movement disorders. We review the pharmacotherapy options for restless leg syndrome, Tourette's syndrome, and tardive dyskinesea. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to pa…

On this episode, we discuss the various antiseizure medications used to manage a patient with Epilepsy. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of conti…

On this episode, we are joined by Dr. Bernard Best, PharmD. We are discussing a complex patient case that focuses on sickle cel disease. You can find a copy of the patient case at link below: https://www.corconsultrx.com/handouts Thanks for listening! We want to give a big thanks to our sponsor, High-Powered Medicine. HPM is a book/website database…

On this episode, we discuss the management and treatment of Parkinson's Disease. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit …

On this episode, we discuss some of the new medications that were FDA approved in the first half of 2024. We discuss pivmecillinam (Pivya), ceftobiprole medocaril sodium (Zevtera), vadadustat (Vafseo), sotatercept (Winrevair), aprocitentan (Tryvio), cefepime/enmetazobactam (Exblifep), and more. Cole and I are happy to share that our listeners can c…

On this episode, we review various hormonal contraception options. We disucss the benefits and risks associated with different forms of estrogen and progestins as well as considerations when choosing a contraceptive option based on patient-specific factors. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing educat…

On this episode, we discuss the 2024 acne treatment guidelines that was published by the American Academy of Dermatology. This new set of guidelines was intended as an update to the AAD's 2016 acne guidelines. We review the use of benzoyl peroxide, topical retinoids, topical antibiotics, oral antibiotics, isotretinoin, and other common treatment op…

On this episode, we examine the management of dry eye disease and allergic conjunctivitis. It is important that pharmacists and nurses understand the appropriate use of the medications and when to seek a more thorough work-up. This session seeks to explore these topics, focusing on how this information can best be incorporated into daily medical pr…

On this episode, we discuss the treatment options used for the managment of gastroesophageal reflux disease. We review various types of antacids, H2 blockers, and proton pump inhibitors. We also go over the long term risks associated with these meds. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for…

On this podcast we discuss the management of both hepatitis A and B. We review some background information as well as the criteria for a diagnosis of either. We also go over vaccinations for both viruses and some of the medications used for hep B specifically. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing edu…

On this episode, we are joined by returning guest Dr. Kaleigh Steeleman. Kaleigh is currently a PGY-1 resident at Chaple Hill. She has spent some of her residency time working with functional medicine professionals. She has been particularly interested with in the area of medical CBD, THC, and other synthetic cannabinoids. She provides a quick over…

On this episode we examine systemic lupus erythematosus (SLE). Lupus is a relatively uncommon condition, but is debilitating for those who suffer from it. There are newer medications with unique mechanisms used for this disease. It is important that pharmacists and nurses understand the appropriate use of medications and how to counsel patients on …

On this episode, Cole and I review the 2023 updated atrial fibrillation guidelines. We discuss various rate-control and rythmn-control pharmacotherapy options. We also summarized the acute management vs maintenance therarpy. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast…

On this episode, we review the 2023 Hepatitis C Guidance that was recently published by the Infectious Diseases Society of America (IDSA) and the American Association for the Study of Liver Diseases (AASLD). We discuss the pre-treatment work-up, various treatment options, and drug-drug interactions/clinical pearls for the most commonly used direct-…

On this episode, Cole and I review some of the medications that gained U.S. FDA approval in 2023. We cover a variety of medications that treat various disease states. We focused more on outpatient medications and did not cover new oncology medication approvals. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing ed…

On this episode, my good friend and colleague Alex Hovey, PA-C is sitting in for Cole this episode. We review the treatment of acute rhinosinusitis and pharyngitis. We mention some treatment options for symptom relief in patients with viral sinusitis and viral pharyngitis. We spend the majority of the episode covering the treatment algorithm for ba…

On this episode we review post-traumatic stress disorder (PTSD). We discuss some background information on the disease. Then, we review the various treatment options used to manage PTSD symptoms. To finish the episode, we go through Dr. David N. Osser, MD's PTSD treatment algorithm. Dr. David N. Osser, MD is associate professor of psychiatry at Har…

On this episode, we discuss the 5-HT1A receptor agonist, Exxua (gepirone). Exxua was recently FDA approved for the treatment of general depression. We review the long road this medication took to get approved. We also summarize the dosing, adverse effects, drug-drug interactions, etc for Exxua. Thanks for listening! We want to give a big thanks to …

On this episode, we review the management of chronic kidney disease. We discuss when to use iron vs erythropoietin-stimulating agents (ESAs) for a patient with anemia due to their CKD. We also go over the management of metabolic acidosis, hyperphosphatemia, secondary hyperparathyroidism, etc. Cole and I are happy to share that our listeners can cla…

On this episode we discuss the management of benign prostatic hyperplasia (BPH) as well as overactive bladder (OAB). We review alpha blockers, 5-alpha-reductase inhihibitors, PDE5-inhibitors, anticholinergics, and beta 3 agonists. We close by discussing the best treatment options for patients with controlled BPH symptoms who are still experiencing …

On this episode, we review the treatment of both uncomplicated and complicated urinary tract infections (UTIs). We also use this episode to refresh some clinical pearls for the various antibiotics that are used when treating a UTI. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this …

On this episdoe, we are joined by Dr. Alex Poppen, PharmD, the author of High Powered Medicine. HPM is a book that summarizes over 150 landmark clinical trials. We discuss how Alex came up with the idea for the book as well as how he got it published. We finish the episode with a quick review of the LoDoCo2 trial looking at colchicine for CV risk r…

On this episode, we discuss both treating an acute gout flare and chronic management of gout. We discuss colchicine, NSAIDS, corticosteroids, canakinumab, xanthine oxidase inhibitors, uricosurics, URAT-1 inhibitor, and more. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast…

On this episode, we review pharmacotherapy options for managing osteoarthritis pain. We focus primarily on on hand, knee, and hip OA. We cover NSAIDS, COX2 inhibitors, topical capsaicin, intra-articular corticosteroids, intra-articular hyaluronic acid, duloxetine, and more. Cole and I are happy to share that our listeners can claim ACPE-accredited …

On this episode, we review the medications that are FDA approved for weight loss. We also review recent data on high dose oral semaglutide and injectable tirzepatide. We end by looking at drugs that are currently in the pipeline with unique mechanisms of action. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing e…

On this episode, we are joined by Dr. Brian Gilbert, PharmD, BCCCP, FCCM, FNCS, to compare and contrast alteplase (tPA) versus tenecteplase (TNK-tPA) in the setting ischemic stroke. Brian is an emergency medicine clinical pharmacy specialist at Wesley Medical Center. He also serves as the PGY-2 critical care pharmacy residency program director and …

On this episode, we review the management of hypothyroidism. We focus on levothyroxine as the foundation for a patient treatment. We also discuss the contraversial issue of using synthetic T3 (liothyronine) as an augmentation option for certain patients. The link to the Medscape article, Why the Hesitancy in Recommending Combination T3/T4 Therapy w…

On this episode, we discuss the various treatment options for community acquired pneumonia. We compare and contrast the differences in treating a patient with and without comorbidities in the outpatient setting as well as non-severe and severe CAP in the inpatient setting. We also review some basics for the various antibiotics used in CAP. Cole and…

On this episode, we discuss the management of substance use disorder. We review the pharmacotherapy/psychotherapy options for treating the abuse of alcohol, cocaine, methamphetamine, cannabis, benzodiazepines, and opioids. Make sure to check out our previous episode that covers opioid use disorder specifically. Cole and I are happy to share that ou…

On this episode, we discuss the pharmacotherapy options available for smoking cessation. We start with some background info including pathophysiology, psychology models applicable to smoking cessation, and nicotine dependence assessments. We review varenicline, nicotine replacement therapy in various forms, bupropion SR, and others. Cole and I are …

On this episode, we go over a pharmacotherapy plan for a patient with sickle cell disease, HFrEF, DM2, dyslipidemia, hypertension, POAG, dry eye disease, constipation, GERD, and OSA. Episode 227 Patient Case Information 57-year-old male with sickle cell disease, HFrEF, DM2, dyslipidemia, hypertension, POAG, dry eye disease, constipation, GERD, and …

On this episode, we discuss the considerations and possible changes to a patient's general depression regimen when they have various comorbidities or other circumstances that affect their health . The comorbidities/situations that we cover include: patients with coronary artery disease, patients over the age of 65, patients that are pregnant, chron…